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CHRNA6 gene

Known as: acetylcholine receptor, nicotinic, alpha 6 (neuronal), cholinergic receptor nicotinic alpha 6 subunit, CHRNA6 
National Institutes of Health

Related topics

Related topics

1 relation
Cholinergic Receptors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors
Finding that nicotinic receptors containing the α6 subunit, but not the α4, inhibit chronic pain points to a new set of potential… Expand
2013
2013
Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations
The direct physiological effects that promote nicotine dependence (ND) are mediated by nicotinic acetylcholine receptors (nAChRs… Expand
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Highly Cited
2012
Highly Cited
2012
Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence.
Genome-wide association studies have identified common variation in the CHRNA5-CHRNA3-CHRNB4 and CHRNA6-CHRNB3 gene clusters that… Expand
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2012
2012
Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development
Summary Meso-diencephalic dopaminergic (mdDA) neurons are critical for motor control and cognitive functioning and their loss or… Expand
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Review
2009
Review
2009
Genetic Association of the CHRNA6 and CHRNB3 Genes with Tobacco Dependence in a Nationally Representative Sample
Neuronal nicotinic acetylcholine receptors are activated by both endogenous acetylcholine and exogenous nicotine, making sequence… Expand
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Review
2009
Review
2009
Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer
Defects in genetic and developmental processes are thought to contribute susceptibility to autism and schizophrenia. Presumably… Expand
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2009
2009
SNPs in CHRNA6 and CHRNB3 are associated with alcohol consumption in a nationally representative sample
The CHRNA6 and CHRNB3 genes have been associated with nicotine dependence and early subjective response to nicotine. Here we… Expand
Review
2009
Review
2009
Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions
Nicotine dependence (ND), a major public health challenge, is a complex, multifactorial behavior, in which both genetic and… Expand
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2009
2009
Association of nAChR gene haplotypes with heavy alcohol use and body mass
Co-occurring alcohol and nicotine dependence is common, as is alcohol use disorder and overeating. However, major risk genes for… Expand
2009
2009
The CHRNA6 Gene, Patience, and Voter Turnout
Political scientists have recently explored the genetic basis of political participation. Fowler, Baker & Dawes (2008) recently… Expand
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