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CGP 74588

Known as: CGP-74588, CGP74588 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Platelet-derived growth factor (PDGF) and its receptors (PDGFR) are frequently coexpressed in meningiomas, potentially… Expand
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Highly Cited
2008
Highly Cited
2008
Imatinib at 400 mg daily is standard treatment for chronic myeloid leukemia in chronic phase. We here describe the correlation of… Expand
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Highly Cited
2008
Highly Cited
2008
Purpose: The aim of this study was to explore the effect of several demographic, biological, and pharmacogenetic covariates on… Expand
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Highly Cited
2007
Highly Cited
2007
Imatinib, a protein tyrosine kinase inhibitor, may prevent the growth of glioblastoma cells. Unfortunately, its brain… Expand
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Highly Cited
2005
Highly Cited
2005
Imatinib mesylate (GLEEVEC, GLIVEC, formerly STI571) has demonstrated unprecedented efficacy as first-line therapy for treatment… Expand
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Highly Cited
2004
Highly Cited
2004
The study under discussion was a drug–drug interaction study in which the effect of ketoconazole, a potent CYP450 3A4 inhibitor… Expand
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Highly Cited
2003
Highly Cited
2003
ObjectiveThis study was carried out to investigate the influence of CYP3A induction with rifampicin on imatinib (Gleevec… Expand
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Highly Cited
2003
Highly Cited
2003
Despite the remarkable clinical response rates to imatinib in the treatment of bcr-abl leukemic patients, pharmacokinetic data on… Expand
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Highly Cited
2003
Highly Cited
2003
PurposeImatinib (Glivec) has been established as a highly effective therapy for chronic myeloid leukemia and gastrointestinal… Expand
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Highly Cited
2002
Highly Cited
2002
Signal Transduction Inhibitor 571 (STI571, formerly known as CGP 57148B) or Gleevec received fast track approval by the US Food… Expand
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