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CGP 12177

Known as: 2H-Benzimidazol-2-one, 4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-, CGP-12177 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Agonist-stimulated desensitization of the beta2-adrenergic receptor (beta2AR) is caused by both a potent cAMP-dependent protein… Expand
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2002
2002
1 It has recently been reported that CGP 12177 can act as an agonist at a novel secondary site within the human beta(1… Expand
Highly Cited
1993
Highly Cited
1993
BACKGROUND Positron emission tomography (PET) with 11C-labeled CGP-12177 (CGP) has been shown to have the potential to… Expand
1993
1993
  • M. Law
  • British journal of pharmacology
  • 1993
  • Corpus ID: 24814025
1 Positron emission tomography (PET) with appropriate radioligands offers the possibility of studying receptors non‐invasively in… Expand
Highly Cited
1992
Highly Cited
1992
  • S. Liggett
  • Molecular pharmacology
  • 1992
  • Corpus ID: 43830428
beta 3-Adrenergic receptors (beta 3AR) mediate lipolytic and thermogenic responses in rodent adipose tissues in vitro, and… Expand
Highly Cited
1992
Highly Cited
1992
The presence of a beta-3 adrenoceptor (in addition to the classical beta-1 and beta-2 adrenoceptors) and its involvement in the… Expand
Highly Cited
1991
Highly Cited
1991
The in vivo quantification of myocardial beta-adrenergic receptor has been obtained in five closed-chest dogs using positron… Expand
Highly Cited
1989
Highly Cited
1989
The effect of CGP-12177, originally developed as a radioligand with antagonist properties for binding studies of beta-adrenergic… Expand
Highly Cited
1983
Highly Cited
1983
Isoprenaline treatment of C6-glioma cells induced a fast decrease in the number of beta-adrenergic receptors as determined by… Expand
1983
1983
Two fractions of beta-adrenergic receptors have been separated from desensitized C62B cells by centrifugation on a sucrose… Expand