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CEP-32496

Known as: BRAF(V600E) Inhibitor CEP-32496 
An orally available v-raf murine sarcoma viral oncogene homolog B1 (B-raf) serine/threonine protein kinase inhibitor with potential antineoplastic… 
National Institutes of Health

Papers overview

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2018
2018
CEP-32496, also known as RXDX-105 or Agerafenib, is a new orally active inhibitor for the mutated v-raf murine sarcoma viral… 
2017
2017
11583Background: Lung cancers driven by oncogenic RET fusions have lower response rates to targeted monotherapy such as… 
2012
2012
Mutations in the BRAF gene have been identified in approximately 7% of cancers, including 60% to 70% of melanomas, 29% to 83% of… 
2012
2012
The Ras/RAF/MEK/ERK mitogen-activated protein kinase (MAPK) signaling pathway plays a central role in the regulation of cell… 
2012
2012
Mutations in the BRAF gene have been identified in approximately 7% of cancers, including 60% to 70% of melanomas, 29% to 83% of…