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CELSR2 gene

Known as: KIAA0279, EPIDERMAL GROWTH FACTOR-LIKE 2, CELSR2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Identification of CELSR2 as a novel prognostic biomarker for hepatocellular carcinoma
Background CELSR2 is postulated to be a receptor involved in contact-mediated communication; however, the specific function of… 
2017
2017
CELSR2 is a candidate susceptibility gene in idiopathic scoliosis
A Swedish pedigree with an autosomal dominant inheritance of idiopathic scoliosis was initially studied by genetic linkage… 
Review
2015
Review
2015
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein–Coupled Receptors
The Adhesion family forms a large branch of the pharmacologically important superfamily of G protein–coupled receptors (GPCRs… 
Highly Cited
2014
Highly Cited
2014
Genetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent manner
Significance Connections are crucial to brain function and a variety of molecular systems direct axonal growth during development… 
Highly Cited
2012
Highly Cited
2012
Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.
Highly Cited
2010
Highly Cited
2010
Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus
Ependymal cells form the epithelial lining of cerebral ventricles. Their apical surface is covered by cilia that beat in a… 
2006
2006
Mono-(2-ethylhexyl) phthalate rapidly increases celsr2 protein phosphorylation in HeLa cells via protein kinase C and casein kinase 1.
Phthalates are ubiquitous environmental contaminants that target the fetal and pubertal testis and lead to alterations in… 
Highly Cited
2006
Highly Cited
2006
Expression of planar cell polarity genes during development of the mouse CNS
Atypical cadherin (Celsr3) and the receptor Frizzled3 (Fzd3) are crucial for the development of axonal tracts in the mouse CNS… 
Highly Cited
2002
Highly Cited
2002
Defining the cellular and molecular mechanisms of toxicant action in the testis.
2000
2000
The human homologue of flamingo, EGFL2, encodes a brain-expressed large cadherin-like protein with epidermal growth factor-like domains, and maps to chromosome 1p13.3-p21.1.
The epidermal growth factor (EGF)-like domain, spanning approximately 50 amino acids and with three disulphide bonds, is the… 
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