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CDP 840

Known as: CDP-840, CDP840 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Arylboration of vinylarenes and methyl crotonate with aryl halides and bis(pinacolato)diboron by cooperative Pd/Cu catalysis has… Expand
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2014
2014
Some anti-inflammatory medications reduce alcohol consumption in rodent models. Inhibition of phosphodiesterases (PDE) increases… Expand
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Highly Cited
2006
Highly Cited
2006
RationalePhosphodiesterase-4 (PDE4) has two conformation states based on rolipram binding, the high-affinity rolipram binding… Expand
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2006
2006
Emergence of library-based approaches have changed the way of developing new functional molecules in materials science and… Expand
2005
2005
A rapid synthesis of CDP840 (a potential therapeutic agent for asthma), using 2-pyrimidyl vinyl sulfide as a platform, has been… Expand
Highly Cited
2003
Highly Cited
2003
The carbonyl group occupies a position of central importance in organic synthesis as it allows ready functionalization, for… Expand
2002
2002
The discovery, synthesis and biological activity of a series of triarylethane phosphodiesterase 4 inhibitors is described… Expand
Highly Cited
1997
Highly Cited
1997
Recent studies have suggested that theophylline, a nonspecific phospho-diesterase inhibitor, has useful anti-inflammatory actions… Expand
Highly Cited
1996
Highly Cited
1996
1 The novel tri‐aryl ethane CDP840, is a potent and selective inhibitor of cyclic AMP phosphodiesterase type 4 (PDE 4) extracted… Expand
1996
1996
1 The activity of CDP840, a novel, potent and selective cyclic nucleotide phosphodiesterase type 4 (PDE 4) inhibitor, was… Expand