CDK5 protein, human

Known as: Tau Protein Kinase II Catalytic Subunit, Cyclin-Dependent Kinase 5, PSSALRE protein, human 
Cyclin-dependent kinase 5 (292 aa, ~33 kDa) is encoded by the human CDK5 gene. This protein plays a role in protein phosphorylation and may be… (More)
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Since the identification of cyclin-dependent kinase-5 (Cdk5) as a tau kinase and member of the Cdk family almost 20 years ago… (More)
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Review
2010
Review
2010
Alzheimer's disease (AD) is characterized by cognitive impairment, progressive neurodegeneration and formation of amyloid-beta… (More)
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Highly Cited
2008
Highly Cited
2008
Homeostatic plasticity keeps neuronal spiking output within an optimal range in the face of chronically altered levels of network… (More)
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Highly Cited
2008
Highly Cited
2008
Anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin ligase that destabilizes cell cycle proteins, is activated by Cdh1… (More)
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Highly Cited
2003
Highly Cited
2003
CA1 pyramidal neurons degenerate after transient forebrain ischemia, whereas neurons in other regions of the hippocampus remain… (More)
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Highly Cited
2003
Highly Cited
2003
Repeated exposure to cocaine produces an enduring increase in dendritic spine density in adult rat nucleus accumbens. It has been… (More)
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Highly Cited
2002
Highly Cited
2002
Caffeine has been imbibed since ancient times in tea and coffee, and more recently in colas. Caffeine owes its psychostimulant… (More)
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2002
2002
Hyperphosphorylated tau is a major component of neurofibrillary tangles, one of the hallmarks of Alzheimer's disease. CDK5 is a… (More)
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Highly Cited
2001
Highly Cited
2001
The bis-indole indirubin is an active ingredient of Danggui Longhui Wan, a traditional Chinese medicine recipe used in the… (More)
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Highly Cited
2001
Highly Cited
2001
CDK5 plays an indispensable role in the central nervous system, and its deregulation is involved in neurodegeneration. We report… (More)
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