CDC6 protein, human

Known as: Cell Cycle Controller CDC6, Cell Division Cycle 6 Homolog, CDC18L 
Cell division control protein 6 homolog (560 aa, ~63 kDa) is encoded by the human CDC6 gene. This protein is involved in the mediation of DNA… (More)
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Cell division cycle 6 (CDC6) is an essential regulator of DNA replication in eukaryotic cells. Its best-characterized function is… (More)
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Highly Cited
2007
Highly Cited
2007
The Cdc6 protein is an essential component of pre-replication complexes (preRCs), which assemble at origins of DNA replication… (More)
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Highly Cited
2006
Highly Cited
2006
Loading of the Mcm2-7 DNA replicative helicase onto origin-proximal DNA is a critical and tightly regulated event during the… (More)
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Highly Cited
2005
Highly Cited
2005
AIM To analyse and compare expression patterns of three potential biomarkers-p16(INK4A), CDC6, and MCM5-and evaluate their use as… (More)
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Highly Cited
2001
Highly Cited
2001
Studies on the CDC6 protein, which is crucial to the control of DNA replication in yeast and animal cells, are lacking in plants… (More)
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Highly Cited
1999
Highly Cited
1999
Cyclin-dependent kinases (CDKs) are essential for regulating key transitions in the cell cycle, including initiation of DNA… (More)
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Highly Cited
1998
Highly Cited
1998
Cdc6 has a critical regulatory role in the initiation of DNA replication in yeasts, but its function in mammalian cells has not… (More)
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Highly Cited
1997
Highly Cited
1997
In eukaryotic cells, firing of DNA replication origins normally does not recur until after M phase. This characteristic is… (More)
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Highly Cited
1996
Highly Cited
1996
In eukaryotic cells, DNA replication is confined to a discrete period of the cell cycle and does not usually recur until after… (More)
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Highly Cited
1995
Highly Cited
1995
S phase entry depends on cyclin-dependent kinases whose activation during late G1 due partly to the synthesis of unstable cyclin… (More)
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