CDC25A protein, human

Known as: cell division cycle 25A protein, human, Cell Division Cycle 25A Protein Tyrosine Phosphatase, Cell Division Cycle 25A 
M-phase inducer phosphatase 1 (524 aa, ~59 kDa) is encoded by the human CDC25A gene. This protein plays a role in the regulation of both mitosis and… (More)

Topic mentions per year

Topic mentions per year

1993-2017
0102019932017

Papers overview

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Highly Cited
2009
Highly Cited
2009
In this study, we show that NANOG, a master transcription factor, regulates S-phase entry in human embryonic stem cells (hESCs… (More)
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Highly Cited
2009
Highly Cited
2009
The Rb-E2F pathway drives cell cycle progression and cell proliferation, and the molecular strategies safeguarding its activity… (More)
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2009
2009
DNA damage-induced cell-cycle checkpoints have a critical role in maintaining genomic stability. A key target of the checkpoints… (More)
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Highly Cited
2005
Highly Cited
2005
Pten-/- cells display a partially defective checkpoint in response to ionizing radiation (IR). The checkpoint defect was traced… (More)
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2003
2003
PURPOSE AND EXPERIMENTAL DESIGN CDC25 genes are cell cycle-activating phosphatases that positively regulate the activity of… (More)
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Highly Cited
2001
Highly Cited
2001
Estrogens induce proliferation of estrogen receptor (ER)-positive MCF-7 breast cancer cells by stimulating G(1)/S transition… (More)
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2000
2000
Alterations in cell cycle regulating proteins are common in many cancer types. Recent data suggest a possible link between CDC25… (More)
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Highly Cited
1999
Highly Cited
1999
Functional inactivation of the pRB pathway is a very frequent event in human cancer, resulting in deregulated activity of the E2F… (More)
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Highly Cited
1997
Highly Cited
1997
The deregulation of several cell cycle-related genes participates in neoplastic transformation. Cell cycle progression is driven… (More)
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Highly Cited
1995
Highly Cited
1995
Cyclin-dependent kinases (CDKs) are activated by CDC25 phosphatases, which remove inhibitory phosphate from tyrosine and… (More)
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