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CD81 gene

Known as: CD81, TARGET OF ANTIPROLIFERATIVE ANTIBODY 1, TSPAN28 
This gene may play a role in signal transduction.
National Institutes of Health

Related topics

Related topics

5 relations
CD81 antigenImmune responseSignal TransductionStimulation of Cell Proliferation

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CD81 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
EWI-2 and EWI-F Link the Tetraspanin Web to the Actin Cytoskeleton through Their Direct Association with Ezrin-Radixin-Moesin Proteins*
EWI-2 and EWI-F, two members of a novel subfamily of Ig proteins, are direct partners of tetraspanins CD9 (Tspan29) and CD81… 
Review
1998
Review
1998
CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system.
CD81 (TAPA-1) is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It has been… 
Highly Cited
1998
Highly Cited
1998
Regulation of Endothelial Cell Motility by Complexes of Tetraspan Molecules CD81/TAPA-1 and CD151/PETA-3 with α3β1 Integrin Localized at Endothelial Lateral Junctions
Cell-to-cell junction structures play a key role in cell growth rate control and cell polarization. In endothelial cells (EC… 
Highly Cited
1998
Highly Cited
1998
CD81 on B cells promotes interleukin 4 secretion and antibody production during T helper type 2 immune responses.
Mice lacking CD81 (TAPA-1), a widely expressed tetraspanin molecule, have impaired antibody responses to protein antigens. This… 
Highly Cited
1996
Highly Cited
1996
Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29).
Anti-alpha 4 integrin mAb coprecipitated CD81 (TAPA-1), a 25-kDa cell surface protein, from various alpha 4 beta1 -positive… 
Review
1995
Review
1995
The CD19/CR2/TAPA-1 complex of B lymphocytes: linking natural to acquired immunity.
B lymphocytes must respond to low concentrations of antigen despite having low affinity antigen receptors during the primary… 
Highly Cited
1993
Highly Cited
1993
Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes
The CD21/CD19/TAPA-1 complex of B lymphocytes amplifies signal transduction through membrane immunoglobulin (mIg), recruits… 
Highly Cited
1992
Highly Cited
1992
The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules.
CD19 is a member of the Ig superfamily expressed on the surface of B lymphocytes that may be involved in the regulation of B cell… 
Highly Cited
1990
Highly Cited
1990
TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins
A murine monoclonal antibody was identified by its ability to induce a reversible antiproliferative effect on a human lymphoma… 
Highly Cited
1990
Highly Cited
1990
TAPA-1, the target of an antiproliferative antibody, is associated on the cell surface with the Leu-13 antigen.
A murine mAb, 5A6 (IgG1), has been isolated by immunization with a human B lymphoma cell line and screening for growth inhibition… 
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