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CD46 protein, human

Known as: TLX, Trophoblast Leukocyte Common Antigen, trophoblast leucocyte common antigen, human 
Membrane cofactor protein (392 aa, ~44 kDa) is encoded by the human CD46 gene. This protein is involved in the classical complementation pathway… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (2)

CD46 Antigentrophoblast-lymphocyte cross-reactive antigens
CD46 geneCD46 wt AlleleImmunoregulationIntegral Membrane Proteins

Papers overview

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2015
2015
MicroRNA-378 regulates neural stem cell proliferation and differentiation in vitro by modulating Tailless expression.
2012
2012
Engineered measles virus Edmonston strain used as a novel oncolytic viral system against human neuroblastoma through a CD46 and nectin 4-independent pathway.
Review
2001
Review
2001
The cellular receptor for measles virus—elusive no more
The identity of the measles virus receptor has been controversial. Several years ago CD46 was identified as a cellular receptor… 
Highly Cited
1999
Highly Cited
1999
Characterization of the inflammatory response during acute measles encephalitis in NSE-CD46 transgenic mice
1997
1997
Absence of measles virus receptor (CD46) in lesions of subacute sclerosing panencephalitis brains
Abstract In this study we investigated pathological changes of the expression of the measles virus (MV) receptor, CD46, in… 
1997
1997
A 3D model for the measles virus receptor CD46 based on homology modeling, Monte Carlo simulations, and hemagglutinin binding studies
The two terminal complement control protein (CCP) modules of the CD46 glycoprotein mediate measles virus binding. Three… 
Highly Cited
1996
Highly Cited
1996
The N-glycan of the SCR 2 region is essential for membrane cofactor protein (CD46) to function as a measles virus receptor
Membrane cofactor protein (MCP) (CD46), a complement-regulatory protein, serves as a cellular receptor for measles virus. Its… 
1996
1996
Selective expression of a subset of measles virus receptor-competent CD46 isoforms in human brain.
The human cell surface protein CD46 is the main measles virus (MV) receptor. We analyzed the CD46 isoforms expressed in the brain… 
1995
1995
Multiple isoforms of guinea pig decay-accelerating factor (DAF) generated by alternative splicing.
Human decay-accelerating factor (DAF, CD55), which is one of the regulators of complement activation (RCA), prevents complement… 
1987
1987
Antigens of human trophoblast: trophoblast-lymphocyte cross-reactive antigens on platelets.
Human and rabbit antibodies to trophoblast-lymphocyte cross-reactive (TLX) antigens were employed in an enzyme-linked… 
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