CD274 protein, human

Known as: B7 Homolog 1, B7-H1, Pdcd1 Ligand 1 
Programmed cell death 1 ligand 1 (290 aa, ~33 kDa) is encoded by the human CD274 gene. This protein is involved in the mediation of both the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
05019992017

Papers overview

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Highly Cited
2014
Highly Cited
2014
There have been no major advances for the treatment of metastatic urothelial bladder cancer (UBC) in the last 30 years… (More)
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Highly Cited
2008
Highly Cited
2008
The mechanisms of malignant cell transformation caused by the oncogenic, chimeric nucleophosmin (NPM)/anaplastic lymphoma kinase… (More)
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Highly Cited
2006
Highly Cited
2006
Functional impairment of T cells is characteristic of many chronic mouse and human viral infections. The inhibitory receptor… (More)
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Highly Cited
2006
Highly Cited
2006
B7-H1 molecule increases the apoptosis of tumor-reactive T lymphocytes and reduces their immunogenicity. Breast cancer is the… (More)
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Highly Cited
2006
Highly Cited
2006
Tumor-associated macrophages are a prominent component of ovarian cancer stroma and contribute to tumor progression. B7-H4 is a… (More)
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Highly Cited
2005
Highly Cited
2005
Contemporary approaches for vaccination and immunotherapy are often capable of eliciting strong T-cell responses against tumor… (More)
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Highly Cited
2004
Highly Cited
2004
Expression of B7-H1, a costimulating glycoprotein in the B7 family, is normally restricted to macrophage-lineage cells, providing… (More)
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Highly Cited
2003
Highly Cited
2003
Suppression of dendritic cell function in cancer patients is thought to contribute to the inhibition of immune responses and… (More)
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Highly Cited
2002
Highly Cited
2002
B7-H1, a recently described member of the B7 family of costimulatory molecules, is thought to be involved in the regulation of… (More)
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Highly Cited
1999
Highly Cited
1999
The B7 family members B7-1 and B7-2 interact with CD28 and constitute an essential T-cell co-stimulatory pathway in the… (More)
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