CD244 gene

Known as: NATURAL KILLER CELL RECEPTOR 2B4, SLAM FAMILY, MEMBER 4, NATURAL KILLER CELL ACTIVATION-INDUCING LIGAND 
This gene plays a role in leukocyte activation and immune function.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Hematopoietic stem cells (HSCs) and multipotent hematopoietic progenitors (MPPs) are routinely isolated using various markers but… (More)
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Highly Cited
2010
Highly Cited
2010
UNLABELLED Multiple inhibitory receptors may play a role in the weak or absent CD8+ T-cell response in chronic hepatitis B virus… (More)
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Highly Cited
2008
Highly Cited
2008
2B4 belongs to the CD2 family of molecules and is expressed on all NK, gammadelta, and memory CD8(+) (alphabeta) T cells. The… (More)
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Highly Cited
2008
Highly Cited
2008
Rheumatoid arthritis is a chronic autoimmune inflammatory disease with a complex genetic etiology. Members of the signaling… (More)
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Highly Cited
2006
Highly Cited
2006
Freshly isolated, resting natural killer (NK) cells are generally less lytic against target cells than in vitro interleukin 2 (IL… (More)
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Highly Cited
2005
Highly Cited
2005
To improve our ability to identify hematopoietic stem cells (HSCs) and their localization in vivo, we compared the gene… (More)
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Highly Cited
2005
Highly Cited
2005
Triggering of 2B4 (CD244) can induce natural killer (NK)-cell activation, costimulation, or even inhibition of NK-cell activity… (More)
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Highly Cited
2003
Highly Cited
2003
A dynamic balance of positive and negative signals regulates target cell lysis by natural killer (NK) cells upon engagement of a… (More)
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Review
2001
Review
2001
2B4 is a member of the CD2 subset of the immunoglobulin superfamily molecules expressed on natural killer (NK) cells and other… (More)
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Highly Cited
2000
Highly Cited
2000
Natural cytotoxicity receptors (NKp46, NKp44 and NKp300) play a predominant role in human NK cell triggering during natural… (More)
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