CCR3 protein, human

Known as: C-C Chemokine Receptor Type 3, CCR3, CC-CKR-3 
C-C chemokine receptor type 3 (355 aa, ~41 kDa) is encoded by the human CCR3 gene. This protein plays a role in eosinophil chemotaxis.
National Institutes of Health

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Highly Cited
2002
Highly Cited
2002
CCR3 is a chemokine receptor initially thought specific to eosinophils but subsequently identified on TH2 cell subsets, basophils… (More)
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Highly Cited
2002
Highly Cited
2002
The CC chemokine receptor 3 (CCR3) is expressed by eosinophils, mast cells, and Th2 cells. We used CCR3(-/-) mice to assess the… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Unstable atherosclerotic lesions typically have an abundant inflammatory cell infiltrate, including activated T cells… (More)
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Highly Cited
1999
Highly Cited
1999
Mast cells (MCs) arise in situ from circulating stem cell factor (SCF)-dependent committed progenitors (PrMCs) and accumulate at… (More)
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Highly Cited
1999
Highly Cited
1999
Microglia are the main human immunodeficiency virus (HIV) reservoir in the central nervous system and most likely play a major… (More)
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Highly Cited
1998
Highly Cited
1998
T helper cells type 1 (Th1s) that produce interferon-gamma predominantly mediate cellular immune responses and are involved in… (More)
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Highly Cited
1997
Highly Cited
1997
Chemokines bind and signal through G-protein coupled seven transmembrane receptors. Various chemokine receptors are expressed on… (More)
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Highly Cited
1997
Highly Cited
1997
Eosinophil leukocytes express high numbers of the chemokine receptor CCR3 which binds eotaxin, monocyte chemotactic protein (MCP… (More)
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Highly Cited
1997
Highly Cited
1997
A novel human CC chemokine consisting of 78 amino acids and having a molecular mass of 8,778.3 daltons (VVIPSPCCMF FVSKRIPENR… (More)
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Highly Cited
1997
Highly Cited
1997
Eotaxin is a newly discovered C-C chemokine which preferentially attracts and activates eosinophil leukocytes by acting… (More)
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