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CCDC170 gene

Known as: coiled-coil domain containing 170, bA282P11.1, CCDC170 
This gene may play a role in bone development.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
BRCA1-associated R-loop affects transcription and differentiation in breast luminal epithelial cells
Abstract BRCA1-associated basal-like breast cancer originates from luminal progenitor cells. Breast epithelial cells from cancer… Expand
Highly Cited
2017
Highly Cited
2017
Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism
Endometriosis is a heritable hormone-dependent gynecological disorder, associated with severe pelvic pain and reduced fertility… Expand
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2017
2017
The Protein Encoded by the CCDC170 Breast Cancer Gene Functions to Organize the Golgi-Microtubule Network
Genome-Wide Association Studies (GWAS) and subsequent fine-mapping studies (> 50) have implicated single nucleotide polymorphisms… Expand
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2017
2017
A Pilot Genome-Wide Association Study in Postmenopausal Mexican-Mestizo Women Implicates the RMND1/CCDC170 Locus Is Associated with Bone Mineral Density
To identify genetic variants influencing bone mineral density (BMD) in the Mexican-Mestizo population, we performed a GWAS for… Expand
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Highly Cited
2016
Highly Cited
2016
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
We analyzed 3,872 common genetic variants across the ESR1 locus (encoding estrogen receptor α) in 118,816 subjects from three… Expand
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2016
2016
Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density
BackgroundOsteoporosis is a common and debilitating bone disease that is characterised by a low bone mineral density (BMD), a… Expand
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2015
2015
Association of five single nucleotide polymorphisms at 6q25.1 with breast cancer risk in northwestern China.
CCDC170 and ESR1, located at 6q25.1, were associated with breast cancer (BC) risk by genome-wide association studies. Our goal… Expand
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Highly Cited
2014
Highly Cited
2014
Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of estrogen-receptor positive breast cancers
Characterizing the genetic alterations leading to the more aggressive forms of estrogen receptor positive (ER+) breast cancers… Expand
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2014
2014
Evaluation of functional genetic variants at 6q25.1 and risk of breast cancer in a Chinese population
IntroductionSingle-nucleotide polymorphisms (SNPs) at 6q25.1 that are associated with breast cancer susceptibility have been… Expand
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2014
2014
Multigene pathway‐based analyses identify nasopharyngeal carcinoma risk associations for cumulative adverse effects of TERT‐CLPTM1L and DNA double‐strand breaks repair
The genetic etiology of nasopharyngeal carcinoma (NPC) and mechanisms for inherited susceptibility remain unclear. To examine… Expand
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