Semantic Scholar uses AI to extract papers important to this topic.
Abstract BRCA1-associated basal-like breast cancer originates from luminal progenitor cells. Breast epithelial cells from cancer… Expand Endometriosis is a heritable hormone-dependent gynecological disorder, associated with severe pelvic pain and reduced fertility… Expand Genome-Wide Association Studies (GWAS) and subsequent fine-mapping studies (> 50) have implicated single nucleotide polymorphisms… Expand To identify genetic variants influencing bone mineral density (BMD) in the Mexican-Mestizo population, we performed a GWAS for… Expand We analyzed 3,872 common genetic variants across the ESR1 locus (encoding estrogen receptor α) in 118,816 subjects from three… Expand BackgroundOsteoporosis is a common and debilitating bone disease that is characterised by a low bone mineral density (BMD), a… Expand CCDC170 and ESR1, located at 6q25.1, were associated with breast cancer (BC) risk by genome-wide association studies. Our goal… Expand Characterizing the genetic alterations leading to the more aggressive forms of estrogen receptor positive (ER+) breast cancers… Expand IntroductionSingle-nucleotide polymorphisms (SNPs) at 6q25.1 that are associated with breast cancer susceptibility have been… Expand The genetic etiology of nasopharyngeal carcinoma (NPC) and mechanisms for inherited susceptibility remain unclear. To examine… Expand