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CBFbeta-MYH11 fusion protein

Known as: CBFb-MYH11 Fusion Protein, CBFbeta-SMMHC Fusion Protein, CBFB/MYH11 Fusion Protein 
A fusion protein encoded by the CBFB/MYH11 fusion gene. This protein is comprised of most of the core-binding factor subunit beta fused to the C… Expand
National Institutes of Health

Papers overview

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2015
2015
CBFβ-SMMHC (core-binding factor β-smooth muscle myosin heavy chain), the fusion protein generated by the chromosome 16 inversion… Expand
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Highly Cited
2012
Highly Cited
2012
The karyotype is so far the most important prognostic parameter in acute myeloid leukemia (AML). Molecular mutations have been… Expand
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2009
2009
The core-binding factor (CBF) is a master regulator of developmental and differentiation programs, and CBF alterations are… Expand
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2007
Highly Cited
2005
Highly Cited
2005
The pericentric inversion of chromosome 16, inv(16)(p13q22), is associated with acute myeloid leukemia (AML) subtype M4Eo that is… Expand
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Highly Cited
2004
Highly Cited
2004
Contemporary treatment of pediatric acute myeloid leukemia (AML) requires the assignment of patients to specific risk groups. To… Expand
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2004
2004
Differential stability of control gene and fusion gene transcripts over time may hamper accurate quantification of minimal… Expand
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2003
2003
A prenatal origin of translocations associated with pediatric leukemia has been demonstrated for MLL-AF4 [1][1] in infant… Expand
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Highly Cited
2001
Highly Cited
2001
The RUNX family genes are the mammalian homologs of the Drosophila genes runt and lozenge, and members of this family function as… Expand
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Highly Cited
1998
Highly Cited
1998
The fusion gene CBFB-MYH11 is generated by the chromosome 16 inversion associated with acute myeloid leukemias. This gene encodes… Expand
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