CBFB/MYH11 FUSION GENE

Known as: CBFbeta-MYH11 Fusion Gene, CBFbeta-SMMHC Fusion Gene, CBFbeta/SMMHC Fusion Gene 
A fusion gene that results from a chromosomal inversion inv(16)(p13q22) which fuses the 5' portion of the CBFB gene with the 3' part of the MYH11… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2016
01219982016

Papers overview

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2017
2017
Acute myeloid leukemia (AML) with inv(16)(p13.1q22) or t(16;16)(p13.1;q22) is defined by the World Health Organization (WHO… (More)
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2016
2016
Treatment-related Acute Myeloid Leukemia (t-AML) is among complications which occur after treatment of primary malignancies due… (More)
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2013
2013
The study was aimed to investigate the clinical characteristics of acute myeloid leukemia (AML) with CBFB-MYH11 gene. The… (More)
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2010
2010
It is known that CBFB-MYH11, the fusion gene generated by inversion of chromosome 16 in human acute myeloid leukemia, is… (More)
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2009
2009
The core-binding factor (CBF) is a master regulator of developmental and differentiation programs, and CBF alterations are… (More)
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2008
2008
The core-binding factor (CBF)-associated leukemia fusion protein CBFbeta-SMMHC impairs myeloid and lymphoid differentiation. By… (More)
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2006
2006
The t(16:16) and inv(16) are associated with FAB M4Eo myeloid leukemias and result in fusion of the CBFB gene to the MYH11 gene… (More)
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2003
2003
The core-binding factor (CBF) leukemias comprise acute myeloid leukemia (AML) with t(8;21) and inv(16)/t(16;16), characterized by… (More)
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2002
2002
In CBFbeta-SMMHC, core binding factor beta (CBFbeta) is fused to the alpha-helical rod domain of smooth muscle myosin heavy chain… (More)
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1998
1998
CBFbeta-SMMHC is expressed in M4Eo acute myeloid leukemia (AML) as a result of inv(16), but how it contributes to leukemogenesis… (More)
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