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The lowest free-energy conformations are identified by structure clustering. A second round of assembly simulation is conducted… Expand We present the assessment of predictions for Template‐Free Modeling in CASP10 and a report on the first ROLL experiment wherein… Expand Background Lung cancer is the leading cause of cancer-related death in the United States. Nearly 50% of patients with stages I… Expand AbstractHuman and mouse natural mutants presenting with lymphoproliferative syndrome and autoimmunity (ALPS) have enlightened the… Expand Caspase 10 (Mch4/FLICE2) is a caspase homologous to caspase 8. A recent report described that inherited CASP10 gene mutations… Expand The rapid discovery of a great number of caspases, together with multiple control points of their activation, proceeds well ahead… Expand Although the commonly activated death protease caspase-3 appears not to be essential for apoptosis during development except in… Expand CASP-8 and CASP-10, members of a cysteine protease family that participates in apoptosis, interact with MORT1/FADD, an adapter… Expand Emerging evidence suggests that an amplifiable protease cascade consisting of multiple aspartate specific cysteine proteases… Expand The Fas/APO-1-receptor associated cysteine protease Mch5 (MACH/FLICE) is believed to be the enzyme responsible for activating a… Expand