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CACNA2D1 gene

Known as: CALCIUM CHANNEL, L TYPE, ALPHA-2 POLYPEPTIDE, CALCIUM CHANNEL, ALPHA-2/DELTA SUBUNIT, calcium voltage-gated channel auxiliary subunit alpha2delta 1 
 
National Institutes of Health

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Related topics

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CACNA2D3 gene

Papers overview

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2018
2018
α2δ-1 Is Essential for Sympathetic Output and NMDA Receptor Activity Potentiated by Angiotensin II in the Hypothalamus.
Both the sympathetic nervous system and the renin-angiotensin system are critically involved in hypertension development… Expand
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2017
2017
Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility
Glaucoma is a multi-factorial blinding disease in which genetic factors play an important role. Elevated intraocular pressure is… Expand
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2015
2015
PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells.
Tumour-initiating cells (TICs) are advocated to constitute the sustaining force to maintain and renew fully established… Expand
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Highly Cited
2011
Highly Cited
2011
TRESK channel contribution to nociceptive sensory neurons excitability: modulation by nerve injury
BackgroundNeuronal hyperexcitability is a crucial phenomenon underlying spontaneous and evoked pain. In invertebrate nociceptors… Expand
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2011
2011
Changing pattern of gene expression is associated with ventricular myocyte dysfunction and altered mechanisms of Ca2+ signalling in young type 2 Zucker diabetic fatty rat heart.
The association between type 2 diabetes and obesity is very strong, and cardiovascular complications are the major cause of… Expand
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Highly Cited
2010
Highly Cited
2010
Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death.
BACKGROUND L-type calcium channel (LTCC) mutations have been associated with Brugada syndrome (BrS), short QT (SQT) syndrome, and… Expand
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2010
2010
Genetic Polymorphisms of the CACNA2D1 Gene and Their Association with Carcass and Meat Quality Traits in Cattle
The objective of this study was to identify genetic polymorphisms of the CACNA2D1 gene and to analyze associations between SNPs… Expand
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2010
2010
Single nucleotide polymorphism of CACNA2D1 gene and its association with milk somatic cell score in cattle
The objective of the present study was to identify polymorphisms of the CACNA2D1 gene, and to analyze associations between these… Expand
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Highly Cited
2008
Highly Cited
2008
Methylation of the calcium channel-related gene, CACNA2D3, is frequent and a poor prognostic factor in gastric cancer.
BACKGROUND & AIMS The calcium channel voltage-dependent alpha2delta subunit consists of 4 genes, CACNA2D1 to CACNA2D4, of which… Expand
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Highly Cited
1994
Highly Cited
1994
Localization of the gene encoding the alpha 2/delta-subunits of the L-type voltage-dependent calcium channel to chromosome 7q and analysis of the segregation of flanking markers in malignant…
Malignant hyperthermia susceptibility (MHS) is an autosomal dominant disorder of skeletal muscle which manifests as a potentially… Expand
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