CA9 gene

Known as: MEMBRANE ANTIGEN MN, CARBONIC ANHYDRASE IX, MN 
This gene may be involved in cell proliferation and transformation.
National Institutes of Health

Papers overview

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2011
2011
Expression of carbonic anhydrase IX (CA9) was shown to be strongly involved in high incidences of metastasis and poor prognosis… (More)
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Highly Cited
2009
Highly Cited
2009
Acidosis of the tumor microenvironment is typical of a malignant phenotype, particularly in hypoxic tumors. All cells express… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND AND PURPOSE Carbonic anhydrase (CA) IX is suggested to be an endogenous marker of hypoxia. Fluorescent sulfonamides… (More)
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Review
2009
Review
2009
Transcriptional activation by hypoxia is mediated by the hypoxia-inducible factor (HIF) via binding to the hypoxia-responsive… (More)
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Highly Cited
2005
Highly Cited
2005
Oral squamous cell carcinomas (OSCCs), a major public health problem worldwide, are the most common neoplasms of the head and… (More)
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Highly Cited
2002
Highly Cited
2002
Regulation by hypoxia may underlie the expression of vascular endothelial growth factor in bladder cancer. We have compared the… (More)
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Highly Cited
2001
Highly Cited
2001
An acidic extracellular pH is a fundamental property of the malignant phenotype. In von Hippel-Lindau (VHL)-defective tumors the… (More)
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Highly Cited
2000
Highly Cited
2000
The transcriptional complex hypoxia-inducible factor-1 (HIF-1) has emerged as an important mediator of gene expression patterns… (More)
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Highly Cited
1998
Highly Cited
1998
To discover genes involved in von Hippel-Lindau (VHL)-mediated carcinogenesis, we used renal cell carcinoma cell lines stably… (More)
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Highly Cited
1996
Highly Cited
1996
We have isolated, sequenced, and characterized a human MN/CA9 gene. This gene is a novel member of the carbonic anhydrase (CA… (More)
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