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CA 074 methyl ester
Known as:
CA074Me
National Institutes of Health
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Related topics
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2 relations
Narrower (1)
CA-074Me
Broader (1)
Dipeptides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Trans-crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients
R. Tiribuzi
,
L. Crispoltoni
,
+9 authors
A. Orlacchio
Journal of Neurological Sciences
2017
Corpus ID: 3087826
Highly Cited
2015
Highly Cited
2015
Multiple Cathepsins Promote Pro–IL-1β Synthesis and NLRP3-Mediated IL-1β Activation
G. Orlowski
,
Jeff D. Colbert
,
Shruti Sharma
,
M. Bogyo
,
S. Robertson
,
K. Rock
Journal of Immunology
2015
Corpus ID: 23340411
Sterile particles induce robust inflammatory responses that underlie the pathogenesis of diseases like silicosis, gout, and…
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2014
2014
Role of cathepsin B in regulating migration and invasion of fibroblast‐like synoviocytes into inflamed tissue from patients with rheumatoid arthritis
Bei Tong
,
B. Wan
,
+6 authors
Y. Dai
Clinical and Experimental Immunology
2014
Corpus ID: 1969806
Cathepsin B (CB), an important proteinase that participates in joint destruction in rheumatoid arthritis (RA), exhibits higher…
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Highly Cited
2014
Highly Cited
2014
Brain pyroglutamate amyloid-β is produced by cathepsin B and is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic.
Gregory R Hook
,
Jin Yu
,
T. Toneff
,
M. Kindy
,
V. Hook
Journal of Alzheimer's Disease
2014
Corpus ID: 12487989
Pyroglutamate amyloid-β peptides (pGlu-Aβ) are particularly pernicious forms of amyloid-β peptides (Aβ) present in Alzheimer's…
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Highly Cited
2012
Highly Cited
2012
Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process
Patrick Gonzalez
,
I. Mader
,
+5 authors
S. Fulda
Cell Death and Differentiation
2012
Corpus ID: 19040202
In this study, we report a novel mechanism of action for a cytotoxic derivative of betulinic acid (BA). B10 is a semi-synthetic…
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Highly Cited
2008
Highly Cited
2008
Inhibitors of Cathepsin B Improve Memory and Reduce β-Amyloid in Transgenic Alzheimer Disease Mice Expressing the Wild-type, but Not the Swedish Mutant, β-Secretase Site of the Amyloid Precursor…
V. Hook
,
M. Kindy
,
Gregory R Hook
Journal of Biological Chemistry
2008
Corpus ID: 5171124
Elucidation of Aβ-lowering agents that inhibit processing of the wild-type (WT) β-secretase amyloid precursor protein (APP) site…
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Highly Cited
2006
Highly Cited
2006
New insights on the use of desipramine as an inhibitor for acid ceramidase
S. Elojeimy
,
D. Holman
,
+8 authors
J. Norris
FEBS Letters
2006
Corpus ID: 38349730
Highly Cited
2005
Highly Cited
2005
Inhibition of cathepsin B reduces β-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate β-secretase of Alzheimer's disease
V. Hook
,
T. Toneff
,
+6 authors
T. Reisine
Biological chemistry
2005
Corpus ID: 9038695
Abstract The regulated secretory pathway of neurons is the major source of extracellular Aβ that accumulates in Alzheimer's…
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Highly Cited
2005
Highly Cited
2005
Overexpression of Stefin A in Human Esophageal Squamous Cell Carcinoma Cells Inhibits Tumor Cell Growth, Angiogenesis, Invasion, and Metastasis
Wen-dong Li
,
F. Ding
,
+7 authors
Zhihua Liu
Clinical Cancer Research
2005
Corpus ID: 24997577
Purpose: Evidence is accumulating that an inverse correlation exists between stefin A level and malignant progression. The aim of…
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Highly Cited
1994
Highly Cited
1994
Inhibition of bone resrption by selctive inactivators of cysteine proteinases
P. Hill
,
D. Buttle
,
+4 authors
M. Meikle
Journal of Cellular Biochemistry
1994
Corpus ID: 8732884
Incativators of cystein proteinases (CPs) were tested as inhibitors of bone resorption in vitro and in vivo. The following four…
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