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CA 074 methyl ester

Known as: CA074Me 
 
National Institutes of Health

Papers overview

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2014
2014
Pyroglutamate amyloid-β peptides (pGlu-Aβ) are particularly pernicious forms of amyloid-β peptides (Aβ) present in Alzheimer's… Expand
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2014
2014
Cathepsin B (CB), an important proteinase that participates in joint destruction in rheumatoid arthritis (RA), exhibits higher… Expand
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2012
2012
Abstract The expression of the cysteine protease cathepsin B is increased in early stages of human breast cancer. To assess the… Expand
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Highly Cited
2008
Highly Cited
2008
Elucidation of Abeta-lowering agents that inhibit processing of the wild-type (WT) beta-secretase amyloid precursor protein (APP… Expand
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2008
2008
Cysteine proteases have been shown to be essential virulence factors and drug targets in trypanosomatids and an attractive… Expand
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Highly Cited
2006
Highly Cited
2006
Treatment of different cancer cell lines with desipramine induced a time- and dose-dependent downregulation of acid ceramidase… Expand
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2005
2005
PURPOSE Evidence is accumulating that an inverse correlation exists between stefin A level and malignant progression. The aim of… Expand
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2005
2005
Abstract The regulated secretory pathway of neurons is the major source of extracellular Aβ that accumulates in Alzheimer's… Expand
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2002
2002
Neuroblastoma is the most common type of cancer in infants. In children this tumor is particularly aggressive; despite various… Expand
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1994
1994
Inactivators of cysteine proteinases (CPs) were tested as inhibitors of bone resorption in vitro and in vivo. The following four… Expand
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