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CA 074 methyl ester

Known as: CA074Me 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Sterile particles induce robust inflammatory responses that underlie the pathogenesis of diseases like silicosis, gout, and… Expand
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Highly Cited
2014
Highly Cited
2014
Pyroglutamate amyloid-β peptides (pGlu-Aβ) are particularly pernicious forms of amyloid-β peptides (Aβ) present in Alzheimer's… Expand
Highly Cited
2012
Highly Cited
2012
In this study, we report a novel mechanism of action for a cytotoxic derivative of betulinic acid (BA). B10 is a semi-synthetic… Expand
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Highly Cited
2008
Highly Cited
2008
Elucidation of Aβ-lowering agents that inhibit processing of the wild-type (WT) β-secretase amyloid precursor protein (APP) site… Expand
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Highly Cited
2006
Highly Cited
2006
Treatment of different cancer cell lines with desipramine induced a time‐ and dose‐dependent downregulation of acid ceramidase… Expand
Highly Cited
2005
Highly Cited
2005
Abstract The regulated secretory pathway of neurons is the major source of extracellular Aβ that accumulates in Alzheimer's… Expand
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Highly Cited
2005
Highly Cited
2005
Purpose: Evidence is accumulating that an inverse correlation exists between stefin A level and malignant progression. The aim of… Expand
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Highly Cited
2005
Highly Cited
2005
Purpose: The death ligand TRAIL (tumor necrosis factor-related apoptosis inducing ligand) triggers apoptosis in a variety of… Expand
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2002
2002
Neuroblastoma is the most common type of cancer in infants. In children this tumor is particularly aggressive; despite various… Expand
Highly Cited
1994
Highly Cited
1994
Incativators of cystein proteinases (CPs) were tested as inhibitors of bone resorption in vitro and in vivo. The following four… Expand