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C46/CCR5/P140K Lentiviral Vector-transduced Autologous HSPCs

Autologous CD34-positive, hematopoietic stem progenitor cells (HSPCs) genetically modified with a lentiviral vector expressing short hairpin RNA that… 
National Institutes of Health

Papers overview

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2020
2020
Here we investigated the roles of Rab27a, a player in exosome release, and TRAF3IP2, an inflammatory mediator, in development and… 
2018
2018
Clonal hematopoiesis by hematopoietic stem progenitor cells (HSPCs) that lack an HLA class I allele (HLA- HSPCs) is common in… 
2015
2015
AC133 is a prominent surface marker of CD34+ and CD34− hematopoietic stem/progenitor cell (HSPC) subsets. AC133+ HSPCs contain… 
2015
2015
Hepatocellular carcinoma (HCC) is a major public health problem. Despite new chemotherapeutic treatments, drug resistance remains… 
2013
2013
Cell adhesion and migration are important determinants of homing and development of hematopoietic stem and progenitor cells… 
2013
2013
Hematopoietic cells derived from human embryonic stem cells (hESCs) have a number of potential utilities, including the modeling… 
Review
2011
Review
2011
Under normal conditions, the great majority of hematopoietic stem/progenitors cells (HSPCs) reside in the bone marrow. The number…