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C46/CCR5/P140K Lentiviral Vector-transduced Autologous HSPCs

Autologous CD34-positive, hematopoietic stem progenitor cells (HSPCs) genetically modified with a lentiviral vector expressing short hairpin RNA that… Expand
National Institutes of Health

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2019
2019
AIMS Cell-based biological pacemakers aim to overcome limitations and side effects of electronic pacemaker devices. We here… Expand
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2018
2018
Clonal hematopoiesis by hematopoietic stem progenitor cells (HSPCs) that lack an HLA class I allele (HLA- HSPCs) is common in… Expand
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2018
2018
C57BL/6N (N) and C57BL/6J (J) mice possess key genetic differences, including a deletion in the Nicotinamide nucleotide… Expand
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2015
2015
AC133 is a prominent surface marker of CD34+ and CD34− hematopoietic stem/progenitor cell (HSPC) subsets. AC133+ HSPCs contain… Expand
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2015
2015
Hepatocellular carcinoma (HCC) is a major public health problem. Despite new chemotherapeutic treatments, drug resistance remains… Expand
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2015
2015
The human T-cell leukemia retrovirus type-1 (HTLV-1) transforms CD4+ T-lymphocytes and causes adult T-cell leukemia/lymphoma… Expand
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2013
2013
Cell adhesion and migration are important determinants of homing and development of hematopoietic stem and progenitor cells… Expand
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2013
2013
Hematopoietic cells derived from human embryonic stem cells (hESCs) have a number of potential utilities, including the modeling… Expand
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2013
2013
Homing and engraftment of hematopoietic stem and progenitor cells (HSPCs) during bone marrow transplantation are critically… Expand
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Review
2011
Review
2011
Under normal conditions, the great majority of hematopoietic stem/progenitors cells (HSPCs) reside in the bone marrow. The number… Expand
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