C-1748

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2017
01220052017

Papers overview

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2017
2017
Drug resistance is one of the major causes of pancreatic cancer treatment failure. Thus, it is still imperative to develop new… (More)
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2015
2015
The “vitamin E” family consists primarily of four naturally occurring tocopherols (alpha-, beta-, gammaand delta-) and four… (More)
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2014
2014
High CYP3A4 expression sensitizes tumor cells to certain antitumor agents while for others it can lower their therapeutic… (More)
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2013
2013
Induction of proteins involved in drug metabolism and in drug delivery has a significant impact on drug-drug interactions and on… (More)
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2012
2012
The narrow "therapeutic window" of anti-tumour therapy may be the result of drug metabolism leading to the activation or… (More)
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2010
2010
C-1748 is a DNA-binding agent with potent antitumor activity, especially towards prostate and colon carcinoma xenografts in mice… (More)
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2007
2007
Chemotherapy in prostate cancer (CaP) even as an adjunct has not been a success. In this communication, we report the pre… (More)
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2007
2007
Nitroacridines are potent DNA-binding and cytotoxic agents in cancer cells, but could not be developed clinically due to high… (More)
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2006
2006
We have developed a group of 4-substituted-1-nitroacridines with potent anti-tumor activity against prostate cancer and less… (More)
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2005
2005
The anticancer effect of 1-nitro-9-hydroxyethylamino acridine (C-857), a compound belonging to the 1-nitroacridine class, has… (More)
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