Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Buthionine Sulfoximine

Known as: Buthionine Sulfoximine [Chemical/Ingredient], Butanoic Acid, 2-Amino-4-(S-butylsulfonimidoyl)-, S-(3-Amino-3-carboxypropyl)-S-butylsulfoximine 
A synthetic amino acid. Buthionine sulfoximine irreversibly inhibits gamma-glutamylcysteine synthase, thereby depleting cells of glutathione, a… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell differentiation, proliferation… Expand
  • figure 1
  • figure 2
Highly Cited
2009
Highly Cited
2009
BACKGROUND Hysterectomy and bilateral salpingo-oophorectomy (BSO) is the standard surgery for stage I endometrial cancer… Expand
  • figure 1
  • figure 2
  • table 1
  • table 2
  • table 3
Highly Cited
2004
Highly Cited
2004
AbstractClinical application of anticancer agents has been often hampered by toxicity against normal cells, so the achievement of… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
2000
Highly Cited
2000
Mitochondrial respiratory function is impaired in the target tissues of patients with mitochondrial diseases and declines with… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Highly Cited
1995
Highly Cited
1995
From 1969 to 1990, 649 patients with adenocarcinoma of the endometrium were surgically managed by gynecologic oncologists from… Expand
Highly Cited
1992
Highly Cited
1992
Exposure of human ovarian tumor cell lines to cisplatin led to development of cell lines that exhibited increasing degrees of… Expand
  • table 1
  • table 2
  • figure 2
  • figure 1
  • figure 3
Highly Cited
1985
Highly Cited
1985
Abstract The development of acquired resistance to antineoplastic drugs and the associated broad cross-resistance to other agents… Expand
Review
1984
Review
1984
Glutathione, as the chief nonprotein intracellular sulfhydryl, affects the efficacy and interactions of a variety of… Expand
  • table 1
Highly Cited
1979
Highly Cited
1979
Buthionine sulfoximine (S-n-butyl homocysteine sulfoximine), the most potent of a series of analogs of methionine sulfoximine… Expand
  • figure 1
  • figure 2
  • table I