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Burimamide
Known as:
Burimamide [Chemical/Ingredient]
, Thiourea, N-(4-(1H-imidazol-4-yl)butyl)-N'-methyl-
An antagonist of histamine that appears to block both H2 and H3 histamine receptors. It has been used in the treatment of ulcers.
National Institutes of Health
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Related topics
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9 relations
Broader (2)
Anti-Ulcer Agent
Histamine H2 Antagonists
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1996
Highly Cited
1996
Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors.
M. Smit
,
R. Leurs
,
+5 authors
H. Timmerman
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 37338262
Histamine H2 receptors transfected in Chinese hamster ovary (CHO) cells are time- and dose-dependently upregulated upon exposure…
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Highly Cited
1993
Highly Cited
1993
Cimetidine and other H2 receptor antagonists as powerful hydroxyl radical scavengers.
T. Ching
,
G. Haenen
,
A. Bast
Chemico-Biological Interactions
1993
Corpus ID: 9677853
Highly Cited
1990
Highly Cited
1990
Histamine H3 receptor binding sites in rat brain membranes: modulations by guanine nucleotides and divalent cations.
J. Arrang
,
J. Roy
,
J. Morgat
,
W. Schunack
,
J. Schwartz
European Journal of Pharmacology
1990
Corpus ID: 22346502
Highly Cited
1988
Highly Cited
1988
Presynaptic inhibition produced by histamine at nicotinic synapses in enteric ganglia
K. Tamura
,
J. Palmer
,
J. Wood
Neuroscience
1988
Corpus ID: 27279584
Highly Cited
1987
Highly Cited
1987
Autoinhibition of histamine synthesis mediated by presynaptic H3-receptors
J. Arrang
,
M. Garbarg
,
J. Schwartz
Neuroscience
1987
Corpus ID: 21117820
Highly Cited
1985
Highly Cited
1985
Autoregulation of histamine release in brain by presynaptic H3-receptors
J.-M. Arrang
,
M. Garbarg
,
J. Schwartz
Neuroscience
1985
Corpus ID: 24634024
Highly Cited
1978
Highly Cited
1978
Characterization and development of cimetidine as a histamine H2-receptor antagonist
R. Brimblecombe
,
W. Duncan
,
+4 authors
M. Parsons
1978
Corpus ID: 196340308
Highly Cited
1976
Highly Cited
1976
Modulation of cellular-immune responses in vivo and in vitro by histamine receptor-bearing lymphocytes.
R. Rocklin
Journal of Clinical Investigation
1976
Corpus ID: 19662474
Histamine, one of the mediators involved in the IgE-mediated reaction, was demonstrated to influence in vivo and in vitro…
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Highly Cited
1976
Highly Cited
1976
Sites and mechanisms of action of histamine in the central thermoregulatory pathways of the rat
M. Green
,
B. Cox
,
P. Lomax
Neuropharmacology
1976
Corpus ID: 231113
Highly Cited
1975
Highly Cited
1975
Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-and H2-receptor agonists and antagonists.
R. Levi
,
N. Capurro
,
C. Lee
European Journal of Pharmacology
1975
Corpus ID: 4620999
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