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Burimamide

Known as: Burimamide [Chemical/Ingredient], Thiourea, N-(4-(1H-imidazol-4-yl)butyl)-N'-methyl- 
An antagonist of histamine that appears to block both H2 and H3 histamine receptors. It has been used in the treatment of ulcers.
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
SummaryRat brain cortex slices preincubated with 3H-serotonin were superfused with physiological salt solution (containing… Expand
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Highly Cited
2001
Highly Cited
2001
Agonist-independent activity of G-protein-coupled receptor, also referred to as constitutive activity, is a well-documented… Expand
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Highly Cited
1996
Highly Cited
1996
Histamine H2 receptors transfected in Chinese hamster ovary (CHO) cells are time- and dose-dependently upregulated upon exposure… Expand
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Highly Cited
1993
Highly Cited
1993
Hydroxyl radical scavengers are able to compete with deoxyribose for the hydroxyl radicals generated in a reaction mixture. We… Expand
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Highly Cited
1992
Highly Cited
1992
1 The effect of agents which interact with the histamine H3 receptor on potassium‐stimulated tritium release from slices of rat… Expand
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Highly Cited
1987
Highly Cited
1987
The regulation of histamine synthesis was studied on rat brain slices or synaptosomes labeled with L-[3H]histidine… Expand
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Highly Cited
1985
Highly Cited
1985
Regulation of histamine release was studied mainly on brain slices prelabeled with L-[3H]-histidine and depolarized by increased… Expand
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Review
1976
Review
1976
The root and stem decoctions of Sinomenium acutum Rehd. et Wils. (formerly Sinomenium diversifolius Diels, one type of Fang-chi… Expand
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1973
1973
  • P. Eyre
  • British journal of pharmacology
  • 1973
  • Corpus ID: 45518032
Histamine-induced relaxation of the sheep bronchus was antagonized by burimamide but not by mepyramine, indicating the presence… Expand
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1972
1972
Abstract Burimamide is a new type of histamine antagonist; it blocks the H 2 -receptors involved not only in histamine-induced… Expand
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