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Burimamide

Known as: Burimamide [Chemical/Ingredient], Thiourea, N-(4-(1H-imidazol-4-yl)butyl)-N'-methyl- 
An antagonist of histamine that appears to block both H2 and H3 histamine receptors. It has been used in the treatment of ulcers.
National Institutes of Health

Related topics

Related topics

9 relations

Broader (2)

Anti-Ulcer AgentHistamine H2 Antagonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Highly Cited
1996
Highly Cited
1996
Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors.
Histamine H2 receptors transfected in Chinese hamster ovary (CHO) cells are time- and dose-dependently upregulated upon exposure… 
Highly Cited
1993
Highly Cited
1993
Cimetidine and other H2 receptor antagonists as powerful hydroxyl radical scavengers.
Highly Cited
1990
Highly Cited
1990
Histamine H3 receptor binding sites in rat brain membranes: modulations by guanine nucleotides and divalent cations.
Highly Cited
1988
Highly Cited
1988
Presynaptic inhibition produced by histamine at nicotinic synapses in enteric ganglia
Highly Cited
1987
Highly Cited
1987
Autoinhibition of histamine synthesis mediated by presynaptic H3-receptors
Highly Cited
1985
Highly Cited
1985
Autoregulation of histamine release in brain by presynaptic H3-receptors
Highly Cited
1978
Highly Cited
1978
Characterization and development of cimetidine as a histamine H2-receptor antagonist
Highly Cited
1976
Highly Cited
1976
Modulation of cellular-immune responses in vivo and in vitro by histamine receptor-bearing lymphocytes.
  • R. Rocklin
  • Journal of Clinical Investigation
  • 1976
  • Corpus ID: 19662474
Histamine, one of the mediators involved in the IgE-mediated reaction, was demonstrated to influence in vivo and in vitro… 
Highly Cited
1976
Highly Cited
1976
Sites and mechanisms of action of histamine in the central thermoregulatory pathways of the rat
Highly Cited
1975
Highly Cited
1975
Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-and H2-receptor agonists and antagonists.
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