Burimamide

Known as: Burimamide [Chemical/Ingredient], Thiourea, N-(4-(1H-imidazol-4-yl)butyl)-N'-methyl- 
An antagonist of histamine that appears to block both H2 and H3 histamine receptors. It has been used in the treatment of ulcers.
National Institutes of Health

Papers overview

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Highly Cited
1996
Highly Cited
1996
Histamine H2 receptors transfected in Chinese hamster ovary (CHO) cells are time- and dose-dependently upregulated upon exposure… (More)
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Highly Cited
1992
Highly Cited
1992
1. The effect of agents which interact with the histamine H3 receptor on potassium-stimulated tritium release from slices of rat… (More)
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Highly Cited
1989
Highly Cited
1989
The effects of histamine and related drugs on the evoked tritium overflow from superfused rat brain cortex slices preincubated… (More)
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Highly Cited
1988
Highly Cited
1988
Rat brain cortex slices preincubated with 3H-serotonin were superfused with physiological salt solution (containing citalopram… (More)
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1976
1976
1 In isolated heart preparations in which fast sodium channels were blocked by tetrodotoxin (2-4 x 10(-5) M), excitability was… (More)
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1976
1976
Burimamide and metiamide are two histamine H2-receptor antagonists. Evidence is presented that indicates the competitive nature… (More)
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1975
1975
The electrophysiological effects of two potent inhibitors of gastric acid secretion, burimamide and 16,16-dimethyl prostaglandin… (More)
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1973
1973
Histamine-induced relaxation of the sheep bronchus was antagonized by burimamide but not by mepyramine, indicating the presence… (More)
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1973
1973
1. In the isolated perfused guinea-pig heart, the increases in isotonic contraction and in cyclic AMP, produced by 2 μg of… (More)
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1973
1973
1. Anaphylaxis was induced in the isolated heart of the guinea-pig in the presence of burimamide at concentrations of 4 x 10(-5)M… (More)
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