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Primary care clinicians find managing chronic pain challenging. Evidence of long-term efficacy of opioids for chronic… Expand BACKGROUND
Buprenorphine maintenance treatment has been evaluated in randomised controlled trials against placebo medication, and… Expand BACKGROUND
Methadone, a full mu-opioid agonist, is the recommended treatment for opioid dependence during pregnancy. However… Expand OBJECTIVES
To assess the clinical effectiveness and cost-effectiveness of buprenorphine maintenance therapy (BMT) and methadone… Expand BACKGROUND
Buprenorphine has recently been reported to be an alternative to methadone and LAAM for maintenance treatment of… Expand BACKGROUND
Office-based treatment of opiate addiction with a sublingual-tablet formulation of buprenorphine and naloxone has been… Expand The purpose of this study was to characterize the acute effects of buprenorphine, an opioid partial (μ‐agonist, across a wide… Expand OBJECTIVE
To assess the efficacy of buprenorphine for short-term maintenance/detoxification.
A randomized, double-blind… Expand Buprenorphine was evaluated for its abuse potential and utility in treating narcotic addiction. The drug was morphine-like but… Expand 1 Buprenorphine is a highly lipophilic derivative of oripavine. In rodent antinociceptive assays (writhing, tail pressure… Expand