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Buprenorphine

Known as: 21-Cyclopropyl-7alpha-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine, 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (5alpha,7alpha(S))-, Buprenorphine [Chemical/Ingredient] 
A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist… 
National Institutes of Health

Related topics

Related topics

41 relations
168 HR Buprenorphine 0.0075 MG/HR Transdermal System [BuTrans]168 HR Buprenorphine 0.015 MG/HR Transdermal System [BuTrans]Buprenorphine / NaloxoneBuprenorphine 1.8 MG/ML Injectable Solution [Simbadol]

Narrower (11)

BU08070BuTransBunavailHS 599

Broader (2)

Narcotic AntagonistsNarcotics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
The American Psychiatric Publishing Textbook of Substance Abuse Treatment 4Ed
The American Psychiatric Publishing Textbook of Substance Abuse Treatment 4Ed - Libros de Medicina - Toxicologia - 120,65 
2003
2003
Effect of strain and sex on μ opioid receptor-mediated G-protein activation in rat brain
Highly Cited
2001
Highly Cited
2001
Perinatal opioids reduce striatal nerve growth factor content in rat striatum.
Highly Cited
1998
Highly Cited
1998
Alternate-day buprenorphine dosing is preferred to daily dosing by opioid-dependent humans
Abstract Alternate-day buprenorphine dosing was compared to daily dosing in opioid-dependent outpatients and choice of alternate… 
1995
1995
The effect of abdominal surgery on thresholds to thermal and mechanical stimulation in sheep
Highly Cited
1991
Highly Cited
1991
Effects of the analgesic agent tramadol in normal and arthritic rats: comparison with the effects of different opioids, including tolerance and cross-tolerance to morphine.
Highly Cited
1991
Highly Cited
1991
The use of buprenorphine and temazepam by drug injectors.
There has been concern over the growing misuse of buprenorphine and temazepam in Scotland. In interviews with 78 clients of… 
Highly Cited
1984
Highly Cited
1984
Post‐operative analgesia in the dog: a comparison of morphine, buprenorphine and pentazocine
The efficacy of buprenorphine and pentazocine in controlling pain in dogs following orthopaedic surgery was compared with that of… 
Highly Cited
1983
Highly Cited
1983
Pain treatment on outpatient basis utilizing extradural opiates. A danish multicentre study comprising 105 patients
Highly Cited
1983
Highly Cited
1983
Epidural buprenorphine for pain relief after major abdominal surgery
In a controlled trial epidural buprenorphine was compared with epidural morphine as the sole means of analgesia after major… 
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