Breast Cancer, Familial

Known as: Hereditary Breast Cancer, Familial Cancer of Breast, Hereditary Breast Carcinoma 
Breast carcinoma that has developed in relatives of patients with history of breast carcinoma.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Breast cancer is the most common cancer in women in developed countries. To identify common breast cancer susceptibility alleles… (More)
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Highly Cited
2009
Highly Cited
2009
Through complete sequencing of the protein-coding genes in a patient with familial pancreatic cancer, we identified a germline… (More)
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Highly Cited
2008
Highly Cited
2008
A G to C polymorphism (rs2910164) is located within the sequence of miR-146a precursor, which leads to a change from a G:U pair… (More)
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Highly Cited
2007
Highly Cited
2007
Inherited breast cancer is associated with germline mutations in ten different genes in pathways critical to genomic integrity… (More)
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Highly Cited
2002
Highly Cited
2002
CHEK2 (previously known as "CHK2") is a cell-cycle-checkpoint kinase that phosphorylates p53 and BRCA1 in response to DNA damage… (More)
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Highly Cited
2002
Highly Cited
2002
In computing the probability that a woman is a BRCA1 or BRCA2 carrier for genetic counselling purposes, it is important to allow… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Many cases of hereditary breast cancer are due to mutations in either the BRCA1 or the BRCA2 gene. The… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND A few breast cancer cases are attributable to a hereditary predisposition to the disease. We aimed to compare the… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Mutations of the tumor suppressor gene p53 have been identified in breast cancer cell lines, and some breast… (More)
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Highly Cited
1990
Highly Cited
1990
Human breast cancer is usually caused by genetic alterations of somatic cells of the breast, but occasionally, susceptibility to… (More)
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