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Brain Glioblastoma

Known as: Brain Glioblastoma Multiforme, Grade IV Astrocytic Neoplasm of Brain, Grade IV Astrocytic Tumor of the Brain 
A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Therapeutic efficacy of glioblastoma multiforme (GBM) is often severely limited by poor penetration of therapeutics through blood… Expand
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Highly Cited
2014
Highly Cited
2014
Recent studies have identified a class of small non‐coding RNA molecules, named microRNA (miRNA), that is dysregulated in… Expand
Highly Cited
2012
Highly Cited
2012
Though there has been substantial advancement in the knowledge about tumour development and treatment in the past 40 years, the… Expand
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Highly Cited
2012
Highly Cited
2012
  • F. Yang, T. Wong, +4 authors M. Wei
  • Journal of controlled release : official journal…
  • 2012
  • Corpus ID: 205872338
The clinical application of chemotherapy to brain tumors has been severely limited because the blood-brain barrier (BBB) often… Expand
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Highly Cited
2001
Highly Cited
2001
Tumor microvessels differ in structure and metabolic function from normal vasculature, and neoangiogenesis is associated with… Expand
Highly Cited
2000
Highly Cited
2000
The blood–brain barrier is a major obstacle for the chemotherapeutic drugs to effectively reach primary or secondary brain… Expand
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Highly Cited
1999
Highly Cited
1999
The long-term consequences of adenovirus-mediated conditional cytotoxic gene therapy for gliomas remain uncharacterized. We… Expand
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Highly Cited
1998
Highly Cited
1998
Connexins (cx), structural components of gap junction, are believed to play a role in the regulation of cell proliferation and… Expand
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Highly Cited
1996
Highly Cited
1996
The prognosis of brain glioblastoma is still very poor and the median survival time is generally less than 6 months. At present… Expand
Highly Cited
1967
Highly Cited
1967
T HERE is n o sat isfactory t r e a t m e n t of glioblastoma mult i forme of the brain. However , as we are constant ly conf ron… Expand