Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Brain Glioblastoma

Known as: Brain Glioblastoma Multiforme, Grade IV Astrocytic Neoplasm of Brain, Grade IV Astrocytic Tumor of the Brain 
A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly… Expand
National Institutes of Health

Related topics

Related topics

16 relations
AnaplasiaAstrocytesBrainCentral Nervous System
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
PEITC inhibits human brain glioblastoma GBM 8401 cell migration and invasion through the inhibition of uPA, Rho A, and Ras with inhibition of MMP-2, -7 and -9 gene expression.
Glioblastoma is the most aggressive primary brain malignancy, and the efficacy of multimodality treatments remains unsatisfactory… Expand
  • table I
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2014
Highly Cited
2014
MicroRNA-16 inhibits glioma cell growth and invasion through suppression of BCL2 and the nuclear factor-κB1/MMP9 signaling pathway
Recent studies have identified a class of small non-coding RNA molecules, named microRNA (miRNA), that is dysregulated in… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Focused ultrasound and interleukin-4 receptor-targeted liposomal doxorubicin for enhanced targeted drug delivery and antitumor effect in glioblastoma multiforme.
The clinical application of chemotherapy to brain tumors has been severely limited because the blood-brain barrier (BBB) often… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Whole-cell SELEX aptamer-functionalised poly(ethyleneglycol)-poly(ε-caprolactone) nanoparticles for enhanced targeted glioblastoma therapy.
Though there has been substantial advancement in the knowledge about tumour development and treatment in the past 40 years, the… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels. selective targeting of endothelial regulatory protein pigpen.
Tumor microvessels differ in structure and metabolic function from normal vasculature, and neoangiogenesis is associated with… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
High intratumoural accumulation of stealth® liposomal doxorubicin (Caelyx®) in glioblastomas and in metastatic brain tumours
The blood–brain barrier is a major obstacle for the chemotherapeutic drugs to effectively reach primary or secondary brain… Expand
  • figure 1
  • table 1
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for clinical…
The long-term consequences of adenovirus-mediated conditional cytotoxic gene therapy for gliomas remain uncharacterized. We… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43).
Connexins (cx), structural components of gap junction, are believed to play a role in the regulation of cell proliferation and… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Increased survival time in brain glioblastomas by a radioneuroendocrine strategy with radiotherapy plus melatonin compared to radiotherapy alone.
The prognosis of brain glioblastoma is still very poor and the median survival time is generally less than 6 months. At present… Expand
Is this relevant?
Highly Cited
1967
Highly Cited
1967
The treatment of glioblastoma multiforme of the brain.
T HERE is n o sat isfactory t r e a t m e n t of glioblastoma mult i forme of the brain. However , as we are constant ly conf ron… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE