Brain Diseases, Metabolic, Inherited

AKT3 (v-akt murine thymoma viral oncogene homolog 3) is located at chromosome 1q44 and encodes a 479 amino acid protein, a member… Expand

Background: A direct role of sodium channels in pain has recently been confirmed by establishing a monogenic link between SCN9A… Expand

Mitochondrial disorders are caused by defects in mitochondrial or nuclear DNA. Although the existence of large deletions in… Expand

The concept of gene therapy emerged as a way of correcting monogenic inherited diseases by introducing a normal copy of the… Expand

The concept of gene therapy emerged as a way of correcting monogenic inherited diseases by introducing a normal copy of the… Expand

Fetal extracellular DNA is mainly derived from apoptotic bodies of trophoblast. Recent studies have shown size differences… Expand

Myotonic dystrophy (DM) results from the amplification of an unstable CTG repeat in the 3' untranslated region of a transcript… Expand

In a new strain of rat with inherited cataracts, a postnatal increase in serum lipid peroxide level was observed. It reached the… Expand