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BmK IT2 scorpion toxin

Known as: BmK IT2 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Scorpion Venoms

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Allosteric interactions between receptor site 3 and 4 of voltage-gated sodium channels: a novel perspective for the underlying mechanism of scorpion sting-induced pain
BackgroundBmK I, a site-3-specific modulator of voltage-gated sodium channels (VGSCs), causes pain and hyperalgesia in rats… Expand
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2011
2011
Localization of Receptor Site on Insect Sodium Channel for Depressant β-toxin BmK IT2
Background BmK IT2 is regarded as a receptor site-4 modulator of sodium channels with depressant insect toxicity. It also… Expand
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2008
2008
Anticonvulsant effect of BmK IT2, a sodium channel‐specific neurotoxin, in rat models of epilepsy
Background and purpose: The sodium channel is a primary target for treating central nervous system disorders such as epilepsy. In… Expand
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2008
2008
The study of sodium channels involved in pain responses using specific modulators.
  • Yong-hua Ji, T. Liu
  • Sheng li xue bao : [Acta physiologica Sinica]
  • 2008
    • Corpus ID: 7470217
Voltage-gated sodium channels (VGSCs) are transmembrane proteins responsible for generation and conduction of action potentials… Expand
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2007
2007
Suppression by intrathecal BmK IT2 on rat spontaneous pain behaviors and spinal c-Fos expression induced by formalin
The central anti-nociception of BmK IT2, a sodium channel modulator from scorpion Buthus martensi Karsh (BmK) was investigated in… Expand
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2003
2003
Suppressive effects of BmK IT2 on nociceptive behavior and c-Fos expression in spinal cord induced by formalin.
In this study, the suppressive effects of BmK IT2, a kind of Na+ channel-specific modulator from the venom of the scorpion Buthus… Expand
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2001
2001
The inhibitory effects of BmK IT2, a scorpion neurotoxin on rat nociceptive flexion reflex and a possible mechanism for modulating voltage-gated Na+ channels
Buthus martensi Karsch IT2 (BmK IT2), a scorpion neurotoxin, was found to display a biphasic inhibitory effect on the C component… Expand
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2000
2000
The binding of BmK IT2, a depressant insect-selective scorpion toxin on mammal and insect sodium channels
Binding assay of (125)I-BmK IT2, a depressant insect-selective scorpion toxin showed two non-interacting binding sites on insect… Expand
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2000
2000
Antihyperalgesia effect of BmK IT2, a depressant insect-selective scorpion toxin in rat by peripheral administration
The study was undertaken to assess the antihyperalgesia effect of BmK IT2, a sodium channel-specific ligand purified from the… Expand
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1997
1997
Nahm's equations and root systems
A method of deriving solutions to Nahm's equations based on root structure of simple Lie algebras is given. As an illustration of… Expand
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