Blood-Brain Barrier Disruption Chemotherapy

Known as: blood-brain barrier disruption, BBBD Chemotherapy, Blood Brain Barrier Disruption Chemotherapy 
Treatment modality used to increase the delivery of chemotherapeutic agents and monoclonal antibodies to the central nervous system tissue through… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
PURPOSE Primary CNS lymphoma (PCNSL) is confined to the CNS and/or the eyes at presentation and is usually initially treated with… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Review
2008
Review
2008
Noninvasive, transient, and local image-guided blood-brain barrier disruption (BBBD) has been demonstrated with focused… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
PURPOSE It is generally accepted that blood-brain barrier (BBB) failure occurs as a result of CNS diseases, including epilepsy… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2007
2007
BACKGROUND Cerebral metastases are clinically significant in 10% to 30% of patients with neoplasia. Multiple cerebral metastases… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Acoustic emission was monitored during focused ultrasound exposures in conjunction with an ultrasound contrast agent (Optison) in… (More)
Is this relevant?
2005
2005
The prognosis for patients with diffuse pontine gliomas (DPG) remains poor. New aggressive innovative treatments are necessary to… (More)
Is this relevant?
2005
2005
BACKGROUND The treatment of malignant brain tumors is hampered by the presence of the blood-brain barrier, which limits… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND S100beta protein is expressed constitutively by brain astrocytes. Elevated S100beta levels in cerebrospinal fluid and… (More)
Is this relevant?
2003
2003
The CNS is shielded from systemic influences by two separate barriers, the blood-brain barrier (BBB) and the blood-to-CSF barrier… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
1981
1981
Reversible transient osmotic blood-brain barrier disruption was used to increase drug delivery to the brain. Methotrexate was… (More)
Is this relevant?