Skip to search formSkip to main contentSkip to account menu

Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide

Known as: 1H-1,4-Diazepine, 1,1'-(dithiodicarbonothioyl)bis(hexahydro-4-methyl), Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide [Chemical/Ingredient] 
An inhibitor of the last step of noradrenaline biosynthesis.
National Institutes of Health

Related topics

Related topics

7 relations
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Investigation of the mechanism by which L-DOPA induces gnawing in mice.
: Stereotyped behaviour including gnawing was elicited in mice by L-DOPA given after various doses of the decarboxylase inhibitor… 
2005
2005
Antagonism by DL-threo-DOPS of the suppression of a conditioned avoidance response induced by a dopamine-β-Hydroxylase inhibitor
The administration of a dopamine-β-hydroxylase inhibitor, FLA-63 [bis (4-methyl-l-homopiperazinylthiocarbonyl) disulfide], 200 mg… 
2004
2004
The occurrence and functional significance of dopamine in some peripheral adrenergic nerves of the rat
SummaryEndogenous levels of dopamine (DA) were measured in rat salivary glands and hearts using a new sensitive method. In these… 
2004
2004
l-DOPA induced effects on motor activity in mice after inhibition of dopamine-β-hydroxylase
The modification by FLA-63 bis-(4-methyl-1-homopiperazinyl thiocarbonyl)-disulfide (Florvall and Corrodi, 1970), an inhibitor of… 
2004
2004
On the role of brain catecholamines in motor activity: Experiments with inhibitors of synthesis and of monoamine oxidase
Mice were pretreated with the monoamine oxidase inhibitor nialamide, and sixteen hours later the dopamine (DA) β-hydroxylase… 
1987
1987
Effects of decarboxylase inhibitors on muricidal suppression by L-dopa in thiamine deficient rats.
Male Wistar rats maintained on a thiamine deficient diet showed mouse-killing behavior (muricide). On the 30th day of… 
1979
1979
Role of brain amines in the fetal hyperpyrexia caused by tranylcypromine in LiCl-pretreated rats.
Tranylcypromine (TCP), a monoamine oxidase inhibitor, caused a fatal hyperpyrexia in rats pretreated with LiCl once a day for 4… 
1977
1977
Mechanism of inhibition of dopamine beta-hydroxylase evoked by FLA-63. An in vitro study.
Bis-(4-methyl-1-homopiperazinylthiocarbonyl)-disulphide (FLA-63) inhibits in vitro purified bovine adrenal medullary dopamine… 
1975
1975
Role of brain monoamines in release of gonadotropin before proestrus in the cyclic rat.
To determine whether brain monoaminergic neurons are involved in the release of gonadotropins responsible for estrogen increases… 
1973
1973
Further evidence for a central hypotensive action of alpha-methyldopa in both the rat and cat.
1. alpha-Methyldopa (300 mg/kg i.p.) produced a fall in blood pressure in conscious genetic hypertensive rats. Pretreatment with…