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Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide

Known as: 1H-1,4-Diazepine, 1,1'-(dithiodicarbonothioyl)bis(hexahydro-4-methyl), Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide [Chemical/Ingredient] 
An inhibitor of the last step of noradrenaline biosynthesis.
National Institutes of Health

Papers overview

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Review
1983
Review
1983
  • J. Monti
  • Life sciences
  • 1983
  • Corpus ID: 6211369
Abstract The exact role of catecholamines (CA) on REM sleep is still controversial. Lesion studies suggest that norepinephrine… Expand
Highly Cited
1981
Highly Cited
1981
Abstract In male hooded rats, depletion of norepinephrine and dopamine by α-methyl- para -tyrosine (AMT) significantly increased… Expand
Highly Cited
1979
Highly Cited
1979
Immediately following exposure to 60 inescapable shocks, Swiss-Webster mice had significantly reduced hypothalamic norepinephrine… Expand
Highly Cited
1976
Highly Cited
1976
In dogs with gastric fistulas, intragastric pressure was measured with a flaccid ballon containing 500 ml of water. Graded doses… Expand
Highly Cited
1976
Highly Cited
1976
This study was intended to examine the role of hypothalamic norepinephrine (HNE) and dopamine (HDA) in episodic luteinizing… Expand
Highly Cited
1975
Highly Cited
1975
The brain mechanisms mediating amphetamine's suppressive effect on feeding behavior were analyzed in rats with chronically… Expand
Highly Cited
1973
Highly Cited
1973
When administered in the diets of mice, α-methyltyrosine reduced the brain contents of endogenous dopamine and norepinephrine and… Expand
Highly Cited
1973
Highly Cited
1973
Abstract Intraventricular injection of 6-hydroxydopamine resulted in only a temporary decrement of self-stimulation. Treatment… Expand
Highly Cited
1970
Highly Cited
1970
Abstract The synthesis of noradrenaline (NA) in the mouse was inhibited either by blocking dopamine (DA) β-hydroxylase with FLA… Expand
Highly Cited
1969
Highly Cited
1969
Abstract FLA-63, a new and potent inhibitor of dopamine β-hydroxylase, was given i.p. to mice. At different time intervals… Expand