Biguanide antimalarial

Known as: Biguanides, biguanide antimalarials 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2018
0519692018

Papers overview

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2015
2015
The human white adipose tissue (WAT) contains progenitors with cooperative roles in breast cancer (BC) angiogenesis, local and… (More)
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2014
Highly Cited
2014
As the concentrations of highly consumed nutrients, particularly glucose, are generally lower in tumours than in normal tissues… (More)
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Highly Cited
2014
Highly Cited
2014
The biguanide metformin is widely prescribed for Type II diabetes and has anti-neoplastic activity in laboratory models. Despite… (More)
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2014
2014
Phenformin (phenethylbiguanide; an anti-diabetic agent) plus oxamate [lactate dehydrogenase (LDH) inhibitor] was tested as a… (More)
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2013
Highly Cited
2013
Glucose production by the liver is essential for providing a substrate for the brain during fasting. The inability of insulin to… (More)
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2012
2012
In recent decades, the antihyperglycemic biguanide metformin has been used extensively in the treatment of type 2 diabetes… (More)
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2010
Highly Cited
2010
Dysfunctional mTORC1 signaling is associated with a number of human pathologies owing to its central role in controlling cell… (More)
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2008
Highly Cited
2008
As a class, the biguanides induce lactic acidosis, a hallmark of mitochondrial impairment. To assess potential mitochondrial… (More)
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2003
Highly Cited
2003
Biguanides are a class of drugs widely used as oral antihyperglycemic agents for the treatment of type 2 diabetes mellitus, but… (More)
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Highly Cited
1978
Highly Cited
1978
Kinetic parameters of metformin (N,N-dimethylbiguanide), an anti-diabetic reported to be associated with a lower number of… (More)
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