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Bifunctional Expression Vector Plasmid DNA-bi-shRNA EWS/FLI1 Type 1 Lipoplex

Known as: Pbi-functional shRNA EWS-FLI1 Type 1 Lipoplex, Pbi-functional Short Hairpin RNA EWS/FLI1 Type 1 Lipoplex, Pbi-shRNA EWS/FLI1 Type 1 Lipoplex 
A proprietary plasmid DNA expression vector encoding bi-functional short hairpin RNAs (bi-shRNAs) targeting the identical type 1 translocation… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Cancer stem cells (CSCs) display plasticity and self-renewal properties reminiscent of normal tissue stem cells, but the events… Expand
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Highly Cited
2009
Highly Cited
2009
Ewing sarcoma family of tumors (ESFT) is an undifferentiated neoplasm of the bone and soft tissue. ESFT is characterized by a… Expand
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Highly Cited
2008
Highly Cited
2008
The synthesis, self-assembly, and gelation ability of a series of organogelators based on perylene bisimide (PBI) dyes containing… Expand
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Highly Cited
2007
Highly Cited
2007
The cellular origin of Ewing tumor (ET), a tumor of bone or soft tissues characterized by specific fusions between EWS and ETS… Expand
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Highly Cited
2005
Highly Cited
2005
The development of effective, systemic therapies for metastatic cancer is highly desired. We show here that the systemic delivery… Expand
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Highly Cited
2005
Highly Cited
2005
PURPOSE EWS-FLI1 fusion type, p53 mutation, and homozygous deletion of p16/p14ARF have each been shown to be prognostically… Expand
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Highly Cited
1998
Highly Cited
1998
PURPOSE More than 90% of Ewing's sarcomas (ES) contain a fusion of the EWS and FLI1 genes, due to the t(11;22)(q24;q12… Expand
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Highly Cited
1997
Highly Cited
1997
The translocation t(11;22) is a common chromosomal abnormality detected both in Ewing's sarcoma and in primitive neuroectodermal… Expand
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Highly Cited
1994
Highly Cited
1994
The 5' half of the EWS gene has recently been described to be fused to the 3' regions of genes encoding the DNA-binding domain of… Expand
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Highly Cited
1993
Highly Cited
1993
The 11;22 chromosomal translocation specifically linked to Ewing sarcoma and primitive neuroectodermal tumor results in a… Expand
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