Bifunctional Expression Vector Plasmid DNA-bi-shRNA EWS/FLI1 Type 1 Lipoplex

Known as: Pbi-functional shRNA EWS-FLI1 Type 1 Lipoplex, Pbi-functional Short Hairpin RNA EWS/FLI1 Type 1 Lipoplex, Pbi-shRNA EWS/FLI1 Type 1 Lipoplex 
A proprietary plasmid DNA expression vector encoding bi-functional short hairpin RNAs (bi-shRNAs) targeting the identical type 1 translocation… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
010203019932017

Papers overview

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2011
2011
BACKGROUND Chromosomal translocations generating oncogenic transcription factors are the hallmark of a variety of tumors… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND EWS-FLI1 is a chimeric ETS transcription factor that is, due to a chromosomal rearrangement, specifically expressed in… (More)
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Highly Cited
2009
Highly Cited
2009
The fusion between EWS and ETS family members is a key oncogenic event in Ewing tumors and important EWS-FLI1 target genes have… (More)
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Highly Cited
2009
Highly Cited
2009
Ewing sarcoma family of tumors (ESFT) is an undifferentiated neoplasm of the bone and soft tissue. ESFT is characterized by a… (More)
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2006
2006
Erbin is a member of the LAP (leucine-rich repeat (LRR) and PDZ domain) family. It inhibits Ras-mediated activation of ERK in… (More)
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Highly Cited
2005
Highly Cited
2005
The development of effective, systemic therapies for metastatic cancer is highly desired. We show here that the systemic delivery… (More)
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2005
2005
In all, 85% of Ewing's sarcoma family tumors (ESFT), a neoplasm of unknown histogenesis, express EWS-FLI1 transcription factor… (More)
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2005
2005
A chimeric protein, EWS-Fli1, identified in most Ewing's family tumors (EFTs) has been shown to be associated with the… (More)
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2003
2003
PURPOSE The presence of metastasis is a major prognostic factor in Ewing tumor (ET). The relapse pattern of patients with… (More)
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Highly Cited
1997
Highly Cited
1997
EWS/FLI1, a fusion gene found in Ewing's sarcoma, encodes a transcriptional regulator and promotes cellular transformation by… (More)
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