Bemegride

Known as: Bemegride [Chemical/Ingredient], Ethylmethylglutarimide, Methetharimide 
A CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1955-2016
05101519552015

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12 relations

Broader (4)

AnalepticsCentral Nervous System StimulantsConvulsantsRespiratory System Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Narrower (1)

Megimide

Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
Bemegride
standards characteristics
Central Nervous System Stimulants
Convulsants
chemical synthesis
Respiratory System Agents

Papers overview

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2006
2006
Binding characteristics of levetiracetam to synaptic vesicle protein 2A (SV2A) in human brain and in CHO cells expressing the human recombinant protein.
A specific binding site for the antiepileptic drug levetiracetam (2S-(oxo-1-pyrrolidinyl)butanamide, Keppra) in rat brain… (More)
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2000
2000
Noninvasive cerebral blood volume measurement during seizures using multichannel near infrared spectroscopic topography.
Near infrared spectroscopic topography (NIRS) is widely recognized as a noninvasive method to measure the regional cerebral blood… (More)
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Highly Cited
1995
Highly Cited
1995
The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes.
Levetiracetam ((S)-alpha-ethyl-2-oxo-pyrrolidine acetamide, ucb L059) is a novel potential antiepileptic agent presently in… (More)
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1990
1990
Actions of steroids and bemegride on the GABAA receptor of mouse spinal neurones in culture.
The effects of a synthetic and an endogenous steroid were studied on the GABAA receptors of isolated mouse spinal neurones… (More)
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1982
1982
Antagonism of γ-aminobutyric acid and muscimol by picrotoxin, bicuculline, strychnine, bemegride, leptazol, d-tubocurarine and theophylline in the isolated olfactory cortex
γ-Aminobutyric acid (GABA) applied to neurones in the olfactory cortex slice in vitro, increases input conductance and produces a… (More)
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1980
1980
Decreased convulsant potency of picrotoxin and pentetrazol and enhanced [3H]flunitrazepam cortical binding following stressful manipulations in rats.
Various stressful manipulations in rats (cold-water swim, electric foot-shock administration, imparied access to food reward… (More)
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1979
1979
Discriminative stimulus properties of pentylenetetrazol and bemegride: Some generalization and antagonism tests
In an operant procedure of lever pressing on a FR 10 schedule of food reinforcement, male hooded rats were trained to respond… (More)
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1977
1977
Alcohol-discrimination in gerbils: interactions with bemegride, DH-524, Amphetamine, and delta9-THC.
Male gerbils were trained to discriminate the effects of an injection of alcohol (1.0, 1.5, and 2.0 g/kg) from the nondrug… (More)
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1977
1977
Pentobarbital, diazepam and bemegride: their effects on open-field behavior in the gerbil (Meriones unguiculatus).
Open-field activity was measured in female mongolian gerbils treated with pentobarbital, P-barb. (15 and 20 mg/kg) or diazepam… (More)
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1975
1975
Diazepam as a discriminative cue: its antagonism by bemegride.
Gerbils trained to respond differentially to the presence or absence of diazepam (8.0 mg/kg) in a T-maze showed a dose-related… (More)
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