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Bemegride

Known as: Bemegride [Chemical/Ingredient], Ethylmethylglutarimide, Methetharimide 
A CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of… Expand
National Institutes of Health

Related topics

Related topics

12 relations

Broader (4)

AnalepticsCentral Nervous System StimulantsConvulsantsRespiratory System Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Narrower (1)

Megimide

Papers overview

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Highly Cited
2006
Highly Cited
2006
Binding characteristics of levetiracetam to synaptic vesicle protein 2A (SV2A) in human brain and in CHO cells expressing the human recombinant protein.
A specific binding site for the antiepileptic drug levetiracetam (2S-(oxo-1-pyrrolidinyl)butanamide, Keppra) in rat brain… Expand
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Highly Cited
2000
Highly Cited
2000
Noninvasive cerebral blood volume measurement during seizures using multichannel near infrared spectroscopic topography.
Near infrared spectroscopic topography (NIRS) is widely recognized as a noninvasive method to measure the regional cerebral blood… Expand
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Highly Cited
1995
Highly Cited
1995
The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes.
Levetiracetam ((S)-alpha-ethyl-2-oxo-pyrrolidine acetamide, ucb L059) is a novel potential antiepileptic agent presently in… Expand
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1983
1983
Interaction of the discriminative stimulus properties of diazepam and ethanol in pigeons
One group of pigeons (n = 5) was trained to discriminate between the effects induced by 5.6 mg/kg of diazepam (DZP) and the… Expand
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1980
1980
Decreased convulsant potency of picrotoxin and pentetrazol and enhanced [3H]flunitrazepam cortical binding following stressful manipulations in rats
Various stressful manipulations in rats (cold-water swim, electric foot-shock administration, imparied access to food reward… Expand
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1979
1979
Discriminative stimulus properties of pentylenetetrazol and bemegride: Some generalization and antagonism tests
In an operant procedure of lever pressing on a FR 10 schedule of food reinforcement, male hooded rats were trained to respond… Expand
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1977
1977
Alcohol-discrimination in gerbils: interactions with bemegride, DH-524, Amphetamine, and delta9-THC.
Male gerbils were trained to discriminate the effects of an injection of alcohol (1.0, 1.5, and 2.0 g/kg) from the nondrug… Expand
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1975
1975
Diazepam as a discriminative cue: its antagonism by bemegride.
Gerbils trained to respond differentially to the presence or absence of diazepam (8.0 mg/kg) in a T-maze showed a dose-related… Expand
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1970
1970
Physiological and drug-induced changes in the glycogen content of mouse brain.
1. The effect of the method of killing on the concentration of glycogen in mouse brain was determined. The cerebral glycogen… Expand
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1958
1958
Acute glutethimide (Doriden) poisoning; the use of bemegride (Megimide) and hemodialysis.
Glutethimide (Doriden)* has had an unusually rapid and widespread introduction into clinical medicine as a hypnotic and sedative… Expand
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