Bad protein

Known as: BCL2-Binding Protein, Bcl-XL/Bcl-2-Associated Death Promoter, BCL2-Antagonist of Cell Death 
A pro-apoptotic protein and member of the Bcl-2 protein family that is regulated by PHOSPHORYLATION. Unphosphorylated Bad protein inhibits the… (More)
National Institutes of Health

Papers overview

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Review
2004
Review
2004
Resveratrol, trans-3,5,4'-trihydroxystilbene, was first isolated in 1940 as a constituent of the roots of white hellebore… (More)
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Highly Cited
2004
Highly Cited
2004
Constitutive expression of the Pim-1 kinase prolongs survival of cytokine-deprived FDCP1 cells, partly via maintenance of Bcl-2… (More)
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Highly Cited
2003
Highly Cited
2003
Glycolysis and apoptosis are considered major but independent pathways that are critical for cell survival. The activity of BAD… (More)
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Highly Cited
2000
Highly Cited
2000
The Bcl-2 homology 3 (BH3) domain of prodeath Bcl-2 family members mediates their interaction with prosurvival Bcl-2 family… (More)
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Highly Cited
1999
Highly Cited
1999
Signaling pathways between cell surface receptors and the BCL-2 family of proteins regulate cell death. Survival factors induce… (More)
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Highly Cited
1999
Highly Cited
1999
A mechanism by which the Ras-mitogen-activated protein kinase (MAPK) signaling pathway mediates growth factor-dependent cell… (More)
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Highly Cited
1997
Highly Cited
1997
Growth factors can promote cell survival by activating the phosphatidylinositide-3'-OH kinase and its downstream target, the… (More)
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Highly Cited
1996
Highly Cited
1996
Extracellular survival factors alter a cell's susceptibility to apoptosis, often through posttranslational mechanisms. However… (More)
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Highly Cited
1996
Highly Cited
1996
A green fluorescent protein (GFP)-Raf-1 fusion protein was used to show that Bcl-2 can target this kinase to mitochondria. Active… (More)
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Highly Cited
1995
Highly Cited
1995
To extend the mammalian cell death pathway, we screened for further Bcl-2 interacting proteins. Both yeast two-hybrid screening… (More)
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