Bacterial Artificial Chromosomes

Known as: BAC, BACs (Chromosomes), Artificial Chromosome, Bacterial 
DNA constructs that are composed of, at least, a REPLICATION ORIGIN, for successful replication, propagation to and maintenance as an extra… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Shiaoching Gong,1 Martin Doughty,1 Carroll R. Harbaugh,4 Alexander Cummins,4 Mary E. Hatten,2 Nathaniel Heintz,3 and Charles R… (More)
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Highly Cited
2003
Highly Cited
2003
The mammalian central nervous system (CNS) contains a remarkable array of neural cells, each with a complex pattern of… (More)
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Highly Cited
2000
Highly Cited
2000
A recombination system has been developed for efficient chromosome engineering in Escherichia coli by using electroporated linear… (More)
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Highly Cited
2000
Highly Cited
2000
A rapid method obviating the use of selectable markers to genetically manipulate large DNA inserts cloned into bacterial… (More)
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Highly Cited
2000
Highly Cited
2000
Gammaherpesviruses cause important infections of humans, in particular in immunocompromised patients. Recently, murine… (More)
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Highly Cited
1999
Highly Cited
1999
We present a method to modify bacterial artificial chromosomes (BACs) resident in their host strain. The method is based on… (More)
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Highly Cited
1999
Highly Cited
1999
Whole-genome comparisons of the tubercle bacilli were undertaken using ordered bacterial artificial chromosome (BAC) libraries of… (More)
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Highly Cited
1997
Highly Cited
1997
Escherichia coli-based artificial chromosomes have become important tools for physical mapping and sequencing in various genome… (More)
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Highly Cited
1997
Highly Cited
1997
A strategy for cloning and mutagenesis of an infectious herpesvirus genome is described. The mouse cytomegalovirus genome was… (More)
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Highly Cited
1995
Highly Cited
1995
Fluorescence in situ hybridization (FISH) is a powerful tool for physical mapping in human and other mammalian species. However… (More)
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