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BT-061

Known as: BT-061MAb 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Regulatory T cells (Tregs) represent a subpopulation of CD4+ T cells, which are essential for the maintenance of immunological… Expand
2016
2016
The humanized non‐depleting anti‐CD4 monoclonal antibody Tregalizumab (BT‐061) is able to selectively activate the suppressive… Expand
2015
2015
CD4+CD25+ regulatory T cells (Tregs) represent a specialized subpopulation of T cells, which are essential for maintaining… Expand
2015
2015
Regulatory T cells (Tregs) represent a subset of CD4+ T cells that express the forkhead box protein 3 factor (FOXP3) in their… Expand
2015
2015
Treatment of PBMC with the CD4-specific mAb BT-061 induces CD4 down-modulation of T cells. Here we report that addition of BT-061… Expand
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2014
2014
Background . Regulatory T cells (Tregs) are essential for maintaining normal immune homeostasis. We have previously reported that… Expand
2011
2011
  • M. Ehrenstein
  • Nature Reviews Drug Discovery
  • 2011
  • Corpus ID: 205477578
Pharmaceuticals have entered into an agreement to co-develop BT-061, a humanized CD4-specific monoclonal antibody that is… Expand
2010
2010
Naturally occurring Tregs are essential for maintaining normal immune homeostasis in healthy individuals. In patients with… Expand
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