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BT-061
Known as:
BT-061MAb
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Monoclonal Antibodies
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Tregalizumab – A Monoclonal Antibody to Target Regulatory T Cells
M. König
,
F. Rharbaoui
,
S. Aigner
,
B. Dälken
,
J. Schüttrumpf
Frontiers in Immunology
2016
Corpus ID: 9148242
Regulatory T cells (Tregs) represent a subpopulation of CD4+ T cells, which are essential for the maintenance of immunological…
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2016
2016
High thioredoxin-1 levels in rheumatoid arthritis patients diminish binding and signalling of the monoclonal antibody Tregalizumab
K. Heim
,
B. Dälken
,
+7 authors
M. Gutscher
Clinical & Translational Immunology
2016
Corpus ID: 3513048
The humanized non‐depleting anti‐CD4 monoclonal antibody Tregalizumab (BT‐061) is able to selectively activate the suppressive…
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2015
2015
Boosting regulatory T‐cell function with the humanized CD4‐specific humanized monoclonal antibody Tregalizumab (BT‐061)
S. Humblet-Baron
,
F. Baron
Immunology and Cell Biology
2015
Corpus ID: 1458205
Regulatory T cells (Tregs) represent a subset of CD4+ T cells that express the forkhead box protein 3 factor (FOXP3) in their…
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2015
2015
Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64+ cells
S. Vogel
,
E. Grabski
,
+12 authors
U. Kalinke
Scientific Reports
2015
Corpus ID: 16870413
Treatment of PBMC with the CD4-specific mAb BT-061 induces CD4 down-modulation of T cells. Here we report that addition of BT-061…
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2014
2014
A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway
Bianca Helling
,
M. König
,
+15 authors
J. Schüttrumpf
Immunology and Cell Biology
2014
Corpus ID: 10720215
CD4+CD25+ regulatory T cells (Tregs) represent a specialized subpopulation of T cells, which are essential for maintaining…
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2014
2014
The Effect of a Pro-inflammatory Milieu on Tregalizumab ( BT-061 )-Induced Regulatory T-cell Activity
J. Kubach
,
F. Rharbaoui
,
+4 authors
H. Jonuleit
2014
Corpus ID: 62795480
Background . Regulatory T cells (Tregs) are essential for maintaining normal immune homeostasis. We have previously reported that…
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2010
2010
(1125) - Selective Activation of Naturally Occurring Regulatory T Cells (Tregs) by the Monoclonal Antibody (mAb) BT-061. Markers of Clinical Activity and Early Phase II Results in Patients with…
A. Rudnev
,
Sukanya Ragavan
,
+16 authors
A. Orlov-Morozov
2010
Corpus ID: 74437646
Naturally occurring Tregs are essential for maintaining normal immune homeostasis in healthy individuals. In patients with…
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