BRAF NP_004324.2:p.V600E

Known as: NP_004324.2:p.Val600Glu, BRAF V600E, BRAF p.V600E 
A change in the amino acid residue at position 600 in the serine/threonine protein kinase B-raf protein where valine has been replaced by glutamic… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
PURPOSE To investigate the prognostic value of BRAF V600E mutation for the recurrence of papillary thyroid cancer (PTC… (More)
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Highly Cited
2013
Highly Cited
2013
IMPORTANCE BRAF V600E is a prominent oncogene in papillary thyroid cancer (PTC), but its role in PTC-related patient mortality… (More)
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Highly Cited
2011
Highly Cited
2011
Missense mutations of the V600E type constitute the vast majority of tumor-associated somatic alterations in the v-RAF murine… (More)
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Highly Cited
2011
Highly Cited
2011
Activating mutations of the serine threonine kinase v-RAF murine sarcoma viral oncogene homolog B1 (BRAF) are frequent in benign… (More)
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Highly Cited
2010
Highly Cited
2010
Langerhans cell histiocytosis (LCH) has a broad spectrum of clinical behaviors; some cases are self-limited, whereas others… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE To examine the prevalence of BRAF mutation among thyroid cancer histologic subtypes and determine the association of… (More)
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Highly Cited
2007
Highly Cited
2007
CONTEXT Because very few studies have examined the correlation between BRAF mutations and clinicopathological features of… (More)
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Highly Cited
2007
Highly Cited
2007
CONTEXT BRAF mutations are common in papillary thyroid carcinomas (PTCs). By affecting the expression of genes critically related… (More)
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Highly Cited
2005
Highly Cited
2005
The BRAF V600E mutation has been associated with microsatellite instability and the CpG island methylator phenotype (CIMP) in… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND & AIMS The concept of a CpG island methylator phenotype (CIMP), especially in microsatellite stable colon cancer, is… (More)
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