BR96-doxorubicin immunoconjugate

Known as: cBR96-DOX, DOX-MOAB BR96, cBR96-doxorubicin conjugate 
An antibody-drug conjugate composed of the chimeric monoclonal antibody BR96 chemically linked to the cytotoxic drug doxorubicin. The antibody moiety… (More)

Topic mentions per year

Topic mentions per year

1992-2017
02419922017

Papers overview

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2001
2001
PURPOSE The objective of this study was to evaluate the efficacy of sequencing radiation therapy (RT) and antibody targeted… (More)
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2000
2000
OBJECTIVE To evaluate dose intensification with osmotic blood-brain barrier disruption (BBBD) and the potential use of drug… (More)
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Highly Cited
1999
Highly Cited
1999
PURPOSE BMS-182248-1 (BR96-doxorubicin immunoconjugate) is a chimeric human/mouse monoclonal antibody linked to approximately… (More)
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1997
1997
Purpose: The chimeric BR96–doxorubicin (DOX) immunoconjugate, BMS 182248, has induced remissions and cures of human lung… (More)
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1997
1997
The internalizing monoclonal antibody BR96 was conjugated to the anticancer drug doxorubicin (DOX) using an acid-labile hydrazone… (More)
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Review
1996
Review
1996
Immunoconjugates and immunotoxins are attracting attention as potential cancer therapeutic agents; however, monoclonal antibodies… (More)
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1995
1995
Chimeric BR96-doxorubicin conjugate (BR96-DOX) is an immunoconjugate designed to specifically target and kill certain tumor cells… (More)
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1995
1995
Sodium dodecyl sulfate-capillary gel electrophoresis (SDS-CAGE), the capillary version of SDS-polyacrylamide-based slab gel… (More)
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Highly Cited
1993
Highly Cited
1993
Immunoconjugates (BR96-DOX) were prepared between chimeric monoclonal antibody BR96 and the anticancer drug doxorubicin. The… (More)
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