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BIM 46174

Known as: BIM-46174, BIM46174 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

CysteineImidazoles
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Tetrahydroimidazo[1,2‐a]pyrazine Derivatives: Synthesis and Evaluation as Gαq‐Protein Ligands
Abstract The 5,6,7,8‐tetrahydroimidazo[1,2‐a]pyrazine derivative BIM‐46174 and its dimeric form BIM‐46187 (1) are heterocyclized… 
2019
2019
BIM-46174 fragments as potential ligands of G proteins.
The 5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine derivative BIM-46174 has received attention as Gαq inhibitor. We conducted… 
2016
2016
Characterization of Rimonabant effects on G protein activity
G protein-coupled receptor (GPCRs) is the largest class of cell-surface receptors, and represents today the target of 40% of the… 
2006
2006
Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Galpha/Gbetagamma protein complex.
A large number of hormones and local agonists activating guanine-binding protein-coupled receptors (GPCR) play a major role in… 
2006
2006
Anticancer drugs: Downstream GPCR inhibition
10.1038/nrd2181 Although G-protein-coupled receptors (GPCRs) and their downstream signalling pathways are involved in cancer… 
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