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BIM 23052

Known as: BIM-23052 
 
National Institutes of Health

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2 relations

Broader (1)

Somatostatin
analogs & derivatives

Papers overview

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2019
2019
Synthesis, in vitro biological activity and docking of new analogs of BIM-23052 containing unnatural amino acids
Somatostatin (SST) is an endogenous cyclic tetradecapeptide hormone that exerts multiple biological activities via a family of… Expand
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2011
2011
Central administration of pan-somatostatin agonist ODT8-SST prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats.
BACKGROUND   Activation of brain somatostatin receptors (sst(1-5) ) with the stable pan-sst(1-5) somatostatin agonist, ODT8-SST… Expand
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2000
2000
Intracisternal injection of somatostatin receptor 5-preferring agonists induces a vagal cholinergic stimulation of gastric emptying in rats.
We previously showed that the somatostatin receptor 5 (sst(5))-preferring agonist BIM-23052 injected intracisternally (i.c. ; 0.8… Expand
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1998
1998
Effect of 17beta-estradiol on somatostatin receptor expression and inhibitory effects on growth hormone and prolactin release in rat pituitary cell cultures.
In the present study, we tested whether 17beta-estradiol (E2)-induced PRL sensitivity to somatostatin-14 (SRIF) involves… Expand
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1998
1998
Effect of 17β-Estradiol on Somatostatin Receptor Expression and Inhibitory Effects on Growth Hormone and Prolactin Release in Rat Pituitary Cell Cultures.
In the present study, we tested whether 17β-estradiol (E2)-induced PRL sensitivity to somatostatin-14 (SRIF) involves selective… Expand
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1997
1997
Somatostatin inhibits gastrin release and acid secretion by activating sst2 in dogs.
Somatostatin is a potent inhibitor of gastrin-stimulated acid secretion by activation of somatostatin receptor type 2 (sst2) in… Expand
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1997
1997
Somatostatin inhibition of acid and histamine release by activation of somatostatin receptor subtype 2 receptors in rats.
Peptide analogs of somatostatin with relatively selective binding affinities for specific somatostatin receptor subtypes… Expand
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1995
1995
Somatostatin (SSTR2) receptors mediate phospholipase C-independent Ca2+ mobilization in rat AR42J pancreas cells.
Rat AR42J pancreas cells, which express somatostatin-SSTR2 type receptors, responded to SSTR2-selective somatostatin (SRIF… Expand
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1995
1995
Influence of intracisternal injection of somatostatin analog receptor subtypes 2, 3 and 5 on gastric acid secretion in conscious rats
Somatostatin (SST) and its analogs injected into the CSF induce different gastric acid response patterns. Five SST receptors have… Expand
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1993
1993
Characterization of cloned somatostatin receptors SSTR4 and SSTR5.
The recent molecular cloning of the genes and cDNAs encoding multiple somatostatin (SRIF) receptor subtypes has allowed for the… Expand
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