BIIL 284

Known as: BIIL 284 BS, BIIL-284, BIIL-284 BS 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2014
01219892014

Papers overview

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2015
2015
The C1-C19 building block 46 of halichondrin Bs was synthesized via a selective activation/coupling of β-bromoenone 34 with… (More)
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2014
2014
BACKGROUND A clinical study to investigate the leukotriene B(4) (LTB(4))-receptor antagonist BIIL 284 in cystic fibrosis (CF… (More)
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2007
2007
BACKGROUND Several clinical and experimental lines of evidence suggest that leucotriene B4 (LTB4), an arachidonic acid derivative… (More)
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2007
2007
  • Nature Clinical Practice Rheumatology
  • 2007
A multicenter, randomized, double-blind trial has failed to demonstrate efficacy of BIIL 284— a leukotriene B4 (LTB4) receptor… (More)
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Highly Cited
2005
Highly Cited
2005
Leukotriene B(4) (LTB(4)), a potent leukocyte chemoattractant derived from the 5-lipoxygenase metabolism of arachidonic acid… (More)
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2004
2004
BACKGROUND Leukotriene B4 (LTB(4)) has a key role in the pathophysiology of rheumatoid arthritis (RA). OBJECTIVE To investigate… (More)
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2001
2001
BIIL 284 is a new LTB(4) receptor antagonist. It is a prodrug and has negligible binding to the LTB(4) receptor. However… (More)
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1997
1997
A series of 8-substituted derivatives of 3,7-dimethyl-1-propargylxanthine (DMPX) was synthesized and investigated as A2A… (More)
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1996
1996
The expression of P-glycoprotein (P-gp) in tumor cells causes a multidrug resistance (MDR) phenotype. P-gp has been shown to… (More)
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1989
1989
In a double-blind, placebo-controlled cross-over study acute hemodynamic effects of oral UDCG 115 BS (5 and 10 mg) were… (More)
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