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BGP 15
Known as:
BGP-15
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Oximes
Piperidines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Heat Shock Proteins and Autophagy Pathways in Neuroprotection: From Molecular Bases to Pharmacological Interventions
B. Penke
,
F. Bogár
,
T. Crul
,
M. Sántha
,
Melinda E. Tóth
,
L. Vigh
International journal of molecular sciences
2018
Corpus ID: 43920311
Neurodegenerative diseases (NDDs) such as Alzheimer’s disease, Parkinson’s disease and Huntington’s disease (HD), amyotrophic…
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2016
2016
The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunction
H. Salah
,
M. Li
,
+16 authors
L. Larsson
Science Translational Medicine
2016
Corpus ID: 9916435
BGP-15 reduces ventilation-induced diaphragm dysfunction by improving diaphragm fiber and myosin function and enhancing…
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Highly Cited
2014
Highly Cited
2014
The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice.
G. Sapra
,
Y. Tham
,
+17 authors
J. McMullen
Nature communications
2014
Corpus ID: 5489750
Heart failure (HF) and atrial fibrillation (AF) share common risk factors, frequently coexist and are associated with high…
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2012
2012
The HSP co-inducer BGP-15 can prevent the metabolic side effects of the atypical antipsychotics
Zsuzsanna Literáti-Nagy
,
K. Tory
,
+10 authors
L. Vigh
Cell Stress and Chaperones
2012
Corpus ID: 9999339
Weight gain and dysfunction of glucose and lipid metabolism are well-known side effects of atypical antipsychotic drugs (AAPD…
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Highly Cited
2012
Highly Cited
2012
Hsp72 preserves muscle function and slows progression of severe muscular dystrophy
S. M. Gehrig
,
C. Poel
,
+8 authors
G. Lynch
Nature
2012
Corpus ID: 205228343
Duchenne muscular dystrophy (DMD) is a severe and progressive muscle wasting disorder caused by mutations in the dystrophin gene…
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Highly Cited
2011
Highly Cited
2011
Membrane-Lipid Therapy in Operation: The HSP Co-Inducer BGP-15 Activates Stress Signal Transduction Pathways by Remodeling Plasma Membrane Rafts
Imre Gombos
,
T. Crul
,
+17 authors
I. Horváth
PloS one
2011
Corpus ID: 3277252
Aging and pathophysiological conditions are linked to membrane changes which modulate membrane-controlled molecular switches…
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Highly Cited
2010
Highly Cited
2010
BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury.
G. Nagy
,
A. Szarka
,
+9 authors
J. Mandl
Toxicology and applied pharmacology
2010
Corpus ID: 8321659
It has been recently shown that acute acetaminophen toxicity results in endoplasmic reticulum redox stress and an increase in…
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Highly Cited
2009
Highly Cited
2009
Improvement of insulin sensitivity by a novel drug, BGP-15, in insulin-resistant patients: a proof of concept randomized double-blind clinical trial.
B. Literáti-Nagy
,
E. Kulcsár
,
+8 authors
L. Korányi
Hormone and metabolic research = Hormon- und…
2009
Corpus ID: 206290654
The efficacy and safety of the new drug, BGP-15, were compared with placebo in insulin-resistant patients in a 28-day dose…
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Highly Cited
2002
Highly Cited
2002
BGP-15 - a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity.
I. Racz
,
K. Tory
,
+7 authors
P. Literati-Nagy
Biochemical pharmacology
2002
Corpus ID: 29807061
Nephrotoxicity is one of the major dose limiting side effects of cisplatin chemotherapy. The antitumor and toxic effects are…
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Highly Cited
2000
Highly Cited
2000
BGP-15, a nicotinic amidoxime derivate protecting heart from ischemia reperfusion injury through modulation of poly(ADP-ribose) polymerase.
E. Szabados
,
P. Literati-Nagy
,
Beatrix Farkas
,
B. Sumegi
Biochemical pharmacology
2000
Corpus ID: 9999710
The protective effect of O-(3-piperidino-2-hydroxy-1-propyl)nicotinic amidoxime (BGP-15) against ischemia-reperfusion-induced…
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