BDA-366

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2015-2015
01220152015

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2016
2016
Multiple myeloma (MM) is a heterogeneous plasma cell malignancy and remains incurable. B-cell lymphoma-2 (BCL2) protein… (More)
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Review
2016
Review
2016
Overexpression of B cell lymphoma 2 (Bcl-2) proteins is associated with therapy resistance in various human cancers. Traditional… (More)
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2015
2015
The BH4 domain of Bcl2 is required for its antiapoptotic function, thus constituting a promising anticancer target. We identified… (More)
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2015
2015
  • Cancer discovery
  • 2015
The small molecule BDA-366 selectively inhibits BCL2, converting it to a cell death inducer. 
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