BCL2L11 wt Allele

Known as: BimMEL, BIML, BOD 
Human BCL2L11 wild-type allele is located in the vicinity of 2q13 and is approximately 40 kb in length. This allele, which encodes Bcl-2-like protein… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Protease biology is intimately linked to the functional consequences of substrate cleavage events. Human caspases are a family of… (More)
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Highly Cited
2011
Highly Cited
2011
This study addresses the role of PTEN loss in intrinsic resistance to the BRAF inhibitor PLX4720. Immunohistochemical staining of… (More)
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Highly Cited
2011
Highly Cited
2011
Cancers with specific genetic mutations are susceptible to selective kinase inhibitors. However, there is a wide spectrum of… (More)
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Highly Cited
2008
Highly Cited
2008
The proapoptotic BH3-only protein Bim is established to be an important mediator of signaling pathways that induce cell death… (More)
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Highly Cited
2008
Highly Cited
2008
As a model for defining the role of lysosomal cathepsins in apoptosis, we characterized the action of the lysosomotropic agent… (More)
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Highly Cited
2006
Highly Cited
2006
The current study demonstrates a novel cross-talk mechanism between the TRAIL receptor death signaling pathway and the… (More)
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Highly Cited
2005
Highly Cited
2005
Numerous p53 target genes have been implicated in DNA damage-induced apoptosis signaling, but proapoptotic Bcl-2 (B-cell leukemia… (More)
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Highly Cited
2003
Highly Cited
2003
Both the ERK and phosphatidylinositol 3'-kinase (PI3K) signaling pathways can protect cells from apoptosis following withdrawal… (More)
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Highly Cited
2003
Highly Cited
2003
Despite being one of the earliest recognized and most clinically relevant forms of apoptosis, little is known about the… (More)
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Highly Cited
1966
Highly Cited
1966
THE RECEPTORS AND NERVE CELLS that make up the visual pathway must convey and interpret information on both the form and the… (More)
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