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BCH 4556

Known as: BCH-4556 
National Institutes of Health

Related topics

Related topics

2 relations
Troxatyl

Broader (1)

troxacitabine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Phase II study of troxacitabine (BCH-4556) in patients with advanced and/or metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada-Clinical Trials Group.
PURPOSE A multi-institution phase II study was undertaken by National Cancer Institute of Canada-Clinical Trials Group to… 
Highly Cited
2002
Highly Cited
2002
Phase II study of troxacitabine, a novel dioxolane nucleoside analog, in patients with refractory leukemia.
PURPOSE To investigate the activity of a novel dioxolane L-nucleoside analog, troxacitabine (L-(-)-OddC, BCH-4556), in patients… 
Highly Cited
2001
Highly Cited
2001
Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia.
PURPOSE To investigate the toxicity profile, activity, and pharmacokinetics of a novel L-nucleoside analog, troxacitabine (BCH… 
Highly Cited
2001
Highly Cited
2001
Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.
Troxacitabine (Troxatyl; BCH-4556; (-)-2'-deoxy-3'-oxacytidine), a deoxycytidine analogue with an unusual dioxolane structure and… 
2000
2000
The new dioxolane, (-)-2'-deoxy-3'-oxacytidine (BCH-4556, troxacitabine), has activity against pancreatic human tumor xenografts.
There is a great need for new therapeutic agents for patients with advanced pancreatic cancer. The new dioxolane analogue… 
2000
2000
Comparative study of a novel nucleoside analogue (Troxatyl, troxacitabine, BCH-4556) and AraC against leukemic human tumor xenografts expressing high or low cytidine deaminase activity
Abstract.Purpose: Troxacitabine (β-L-dioxolane cytidine, BCH-4556; Troxatyl, BioChem Pharma Inc.) is a novel nucleoside analogue… 
Highly Cited
2000
Highly Cited
2000
A Novel Action of Human Apurinic/Apyrimidinic Endonuclease
β-l-Dioxolane-cytidine (l-OddC, BCH-4556, Troxacitabine) is a novel unnatural stereochemical nucleoside analog that is under… 
1998
1998
Effect of nucleoside analogue BCH-4556 on prostate cancer growth and metastases in vitro and in vivo.
Prostate carcinoma is a common malignancy among males that results in high morbidity and mortality. Here, we have evaluated the… 
1998
1998
Activity of (-)-2'-deoxy-3'-oxacytidine (BCH-4556) against human tumor colony-forming units.
BACKGROUND BCH-4556 ((-)-2'-deoxy-3'-oxacytidine) is an L-nucleoside analogue shown to have broad preclinical anti-cancer… 
Highly Cited
1997
Highly Cited
1997
Potent antitumor activity of a novel nucleoside analogue, BCH-4556 (beta-L-dioxolane-cytidine), in human renal cell carcinoma xenograft tumor models.
Beta-L-Dioxolane-cytidine (BCH-4556) is a novel anticancer nucleoside analogue with a stereochemically unnatural beta-L… 
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