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BCAR1 protein, human

Known as: Crk-associated substrate, human, BCAR1 Protein, Breast Cancer Anti-Estrogen Resistance 1 Protein 
Encoded by human BCAR1 Gene, conserved ubiquitous 870-amino acid 116 kD cytoplasmic p130CAS (CAS Family) is an adaptor molecule: Ser-region, NH-SH3… 
National Institutes of Health

Related topics

Related topics

20 relations
Adaptor Signaling Protein GeneBCAR1 geneBreast CarcinomaCarcinoma

Broader (1)

Crk-Associated Substrate Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas
Review
2004
Review
2004
Modulation of signalling by Sprouty: a developing story
Sprouty proteins are evolutionarily conserved inducible inhibitors of signalling by receptor tyrosine kinases. They have been… 
Review
2004
Review
2004
The interplay between Src and integrins in normal and tumor biology
Src family nonreceptor protein tyrosine kinases transduce signals that control normal cellular processes such as cell… 
Review
1999
Review
1999
Signaling through focal adhesion kinase.
Highly Cited
1999
Highly Cited
1999
Regulation of Cell Contraction and Membrane Ruffling by Distinct Signals in Migratory Cells
Cell migration and wound contraction requires assembly of actin into a functional myosin motor unit capable of generating force… 
Highly Cited
1998
Highly Cited
1998
CAS/Crk Coupling Serves as a “Molecular Switch” for Induction of Cell Migration
Abstract. Carcinoma cells selected for their ability to migrate in vitro showed enhanced invasive properties in vivo. Associated… 
Highly Cited
1997
Highly Cited
1997
The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions
Pathogenic Yersinia resist uptake by eukaryotic cells by a mechanism involving the virulence protein YopH, a protein tyrosine… 
Highly Cited
1996
Highly Cited
1996
Direct Binding of C-terminal Region of p130 to SH2 and SH3 Domains of Src Kinase (*)
p130 is a major tyrosine-phosphorylated protein that tightly binds v-Crk in v-crk-transformed cells and v-Src in v-src… 
Highly Cited
1995
Highly Cited
1995
Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases
Highly Cited
1994
Highly Cited
1994
A novel signaling molecule, p130, forms stable complexes in vivo with v‐Crk and v‐Src in a tyrosine phosphorylation‐dependent manner.
p47v‐crk (v‐Crk), a transforming gene product containing Src homology (SH)‐2 and ‐3 domains, induces an elevated level of… 
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