Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

BAK1 wt Allele

Known as: Cell Death Inhibitor 1 Gene, BAK, BCL2-Antagonist/Killer 1 wt Allele 
Human BAK1 wild-type allele is located in the vicinity of 6p21.3 and is approximately 8 kb in length. This allele, which encodes Bcl-2 homologous… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Multidomain pro-apoptotic BAX and BAK, once activated, permeabilize mitochondria to trigger apoptosis, whereas anti-apoptotic BCL… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Proapoptotic B-cell lymphoma 2 (BCL-2) antagonist/killer (BAK) and BCL-2–associated X (BAX) form toxic mitochondrial pores in… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Deadly Trio The proteins BAX and BAK act as a key decision point, regulating apoptosis by controlling the permeability of the… Expand
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Endoplasmic reticulum (ER) stress-induced apoptosis has been implicated in the development of multiple diseases. However, the in… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Proapoptotic BCL-2 family members BAX and BAK are required for the initiation of mitochondrial dysfunction during apoptosis and… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
B cell homeostasis is maintained by a balance between the continual generation of new cells and their elimination. Here we show… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Genomic instability is a hallmark of cancer development and progression, and characterizing the stresses that create and the… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The "BH3-only" proteins of the BCL-2 family require "multidomain" proapoptotic members BAX and BAK to release cytochrome c from… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
BACKGROUND Pancreatic cancer is extremely resistant to the induction of apoptosis by chemotherapies; agents that regulate… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
ABSTRACT The BCL-2 family includes both proapoptotic (e.g., BAX and BAK) and antiapoptotic (e.g., BCL-2 and BCL-XL) molecules… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?