BAK1 gene

Known as: BAK-LIKE, BCL2 ANTAGONIST KILLER 1, BAK 
This gene is involved in the regulation of apoptosis by inhibiting cell death.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Octamer-binding transcription factor 4 (OCT4) is a key regulatory gene that maintains the pluripotency and self-renewal… (More)
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Highly Cited
2010
Highly Cited
2010
Paclitaxel (Taxol) is an effective chemotherapeutic agent for treatment of cancer patients. Despite impressive initial clinical… (More)
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Highly Cited
2010
Highly Cited
2010
BAK1 is a leucine-rich repeat receptor-like kinase that functions as a coreceptor with the brassinosteroid (BR) receptor BRI1 and… (More)
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Highly Cited
2010
Highly Cited
2010
The development of selective inhibitors for discrete anti-apoptotic BCL-2 family proteins implicated in pathologic cell survival… (More)
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Highly Cited
2006
Highly Cited
2006
BCL-2 proteins are critical for cell survival and are overexpressed in many tumors. ABT-737 is a small-molecule BH3 mimetic that… (More)
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Highly Cited
2005
Highly Cited
2005
Proapoptotic BCL-2 family members BAX and BAK are required for the initiation of mitochondrial dysfunction during apoptosis and… (More)
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Highly Cited
2003
Highly Cited
2003
BAX and BAK are "multidomain" proapoptotic proteins that initiate mitochondrial dysfunction but also localize to the endoplasmic… (More)
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Highly Cited
2002
Highly Cited
2002
Brassinosteroids regulate plant growth and development through a protein complex that includes the leucine-rich repeat receptor… (More)
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Highly Cited
2001
Highly Cited
2001
Multiple death signals influence mitochondria during apoptosis, yet the critical initiating event for mitochondrial dysfunction… (More)
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Highly Cited
2000
Highly Cited
2000
STUDY DESIGN A prospective, concurrently controlled, randomized, multicenter trial of an anterior Bagby and Kuslich cervical… (More)
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